Abstract：
OBJECTIVE: The study is to evaluate reliability and validity of the short Thai version of Functional Outcome of Sleep Questionnaire (FOSQ-10T), in patients with sleep disordered breathing (SDB).
METHODS: Inclusion criteria were Thai patients with SDB age ≥ 18 years old who had polysomnography results available. Exclusion criteria were patients unable to complete questionnaire for any reason, patients with a history of continuous antidepressant or alcohol use, and underlying disorders including unstable cardiovascular, pulmonary, or neurological conditions. All participants were asked to complete the FOSQ-10 T and Epworth sleepiness scales (ESS). Of these, 38 patients were required to retake FOSQ-10 T at 2-4 weeks later to assess test-retest reliability, and 19 OSA patients treated with CPAP were asked to do so at 4 weeks following therapy to assess questionnaire\'s responsiveness to treatment.
RESULTS: There were 42 participants (24 men, 18 women), with a mean age of 48.3 years. The internal consistency of the FOSQ-10T was good, as indicated by Cronbach\'s alpha coefficient of 0.85. The test-retest reliability was good, as indicated by intraclass correlation coefficient of 0.77. The correlation between the FOSQ-10T and ESS scores (concurrent validity) was moderate (r = - 0.41). The scores of FOSQ-10T significantly increased after receiving adequate CPAP therapy, showing an excellent responsiveness to treatment. However, there was no significant association between FOSQ-10T scores and OSA severity measured by apnea-hypopnea index.
CONCLUSIONS: The FOSQ-10T has good reliability and validity to use as a tool to assess QOL in Thai patients with SDB. It is convenient and potentially useful in both clinical and research settings.
METHODS: Inclusion criteria were Thai patients with SDB age ≥ 18 years old who had polysomnography results available. Exclusion criteria were patients unable to complete questionnaire for any reason, patients with a history of continuous antidepressant or alcohol use, and underlying disorders including unstable cardiovascular, pulmonary, or neurological conditions. All participants were asked to complete the FOSQ-10 T and Epworth sleepiness scales (ESS). Of these, 38 patients were required to retake FOSQ-10 T at 2-4 weeks later to assess test-retest reliability, and 19 OSA patients treated with CPAP were asked to do so at 4 weeks following therapy to assess questionnaire\'s responsiveness to treatment.
RESULTS: There were 42 participants (24 men, 18 women), with a mean age of 48.3 years. The internal consistency of the FOSQ-10T was good, as indicated by Cronbach\'s alpha coefficient of 0.85. The test-retest reliability was good, as indicated by intraclass correlation coefficient of 0.77. The correlation between the FOSQ-10T and ESS scores (concurrent validity) was moderate (r = - 0.41). The scores of FOSQ-10T significantly increased after receiving adequate CPAP therapy, showing an excellent responsiveness to treatment. However, there was no significant association between FOSQ-10T scores and OSA severity measured by apnea-hypopnea index.
CONCLUSIONS: The FOSQ-10T has good reliability and validity to use as a tool to assess QOL in Thai patients with SDB. It is convenient and potentially useful in both clinical and research settings.
摘要：
目的：该研究旨在评估简短的泰国版睡眠功能结果问卷（FOSQ-10T）的信度和效度，睡眠呼吸障碍（SDB）患者。
方法：纳入标准为泰国SDB年龄≥18岁且有多导睡眠图结果的患者。排除标准是患者由于任何原因无法完成问卷，有持续抗抑郁或饮酒史的患者，和潜在的疾病，包括不稳定的心血管疾病，肺,或神经系统疾病。要求所有参与者完成FOSQ-10T和Epworth嗜睡量表（ESS）。其中,38例患者需要在2-4周后重新服用FOSQ-10T，以评估重测可靠性，19例接受CPAP治疗的OSA患者在治疗后4周被要求这样做，以评估问卷对治疗的反应性。
结果：有42名参与者（24名男性，18名妇女），平均年龄48.3岁.FOSQ-10T的内部一致性很好，如Cronbach的α系数0.85所示。测试-重测可靠性良好，如0.77的组内相关系数所示。FOSQ-10T与ESS评分（并发有效性）之间的相关性中等（r=-0.41）。接受适当的CPAP治疗后，FOSQ-10T评分显着增加，表现出对治疗的良好反应。然而,FOSQ-10T评分与呼吸暂停低通气指数测量的OSA严重程度之间无显著相关性.
结论：FOSQ-10T作为评估泰国SDB患者生活质量的工具具有良好的信度和效度。它在临床和研究环境中都是方便且潜在有用的。
方法：纳入标准为泰国SDB年龄≥18岁且有多导睡眠图结果的患者。排除标准是患者由于任何原因无法完成问卷，有持续抗抑郁或饮酒史的患者，和潜在的疾病，包括不稳定的心血管疾病，肺,或神经系统疾病。要求所有参与者完成FOSQ-10T和Epworth嗜睡量表（ESS）。其中,38例患者需要在2-4周后重新服用FOSQ-10T，以评估重测可靠性，19例接受CPAP治疗的OSA患者在治疗后4周被要求这样做，以评估问卷对治疗的反应性。
结果：有42名参与者（24名男性，18名妇女），平均年龄48.3岁.FOSQ-10T的内部一致性很好，如Cronbach的α系数0.85所示。测试-重测可靠性良好，如0.77的组内相关系数所示。FOSQ-10T与ESS评分（并发有效性）之间的相关性中等（r=-0.41）。接受适当的CPAP治疗后，FOSQ-10T评分显着增加，表现出对治疗的良好反应。然而,FOSQ-10T评分与呼吸暂停低通气指数测量的OSA严重程度之间无显著相关性.
结论：FOSQ-10T作为评估泰国SDB患者生活质量的工具具有良好的信度和效度。它在临床和研究环境中都是方便且潜在有用的。
