PDF(Pubmed)
Abstract：
OBJECTIVE: We report the first case of Oropouche fever detected in the border region of Colombia.
METHODS: Using a multiplex real-time polymerase chain reaction (PCR), genetic sequencing and clinical characteristics during the dengue epidemic in 2019, a total of 175 samples were analysed, from cases notified to the system epidemiological surveillance such as dengue.
RESULTS: The Oropouche virus (OROV) isolate from Leticia belongs to lineage 2 according to both M and S genome segments maximum likelihood (ML) analysis, shares a common ancestor with samples obtained in Esmeraldas, Ecuador and Turbaco, Colombia. The patient: a woman resident in the border neighbourhood of the municipality of Leticia had the following symptoms: fever, headache, retro-orbital pain and myalgias.
CONCLUSIONS: This cross-border surveillance can be useful to give an alert about the entry or exit of arboviruses circulation in the region, which are often underreported in public health surveillance systems.
METHODS: Using a multiplex real-time polymerase chain reaction (PCR), genetic sequencing and clinical characteristics during the dengue epidemic in 2019, a total of 175 samples were analysed, from cases notified to the system epidemiological surveillance such as dengue.
RESULTS: The Oropouche virus (OROV) isolate from Leticia belongs to lineage 2 according to both M and S genome segments maximum likelihood (ML) analysis, shares a common ancestor with samples obtained in Esmeraldas, Ecuador and Turbaco, Colombia. The patient: a woman resident in the border neighbourhood of the municipality of Leticia had the following symptoms: fever, headache, retro-orbital pain and myalgias.
CONCLUSIONS: This cross-border surveillance can be useful to give an alert about the entry or exit of arboviruses circulation in the region, which are often underreported in public health surveillance systems.
摘要：
目的：我们报告了在哥伦比亚边境地区发现的首例Oropouche热。
方法：使用多重实时聚合酶链反应（PCR），2019年登革热流行期间的基因测序和临床特征，共分析了175个样本，从通报给系统流行病学监测的病例，如登革热。
结果：根据M和S基因组片段最大似然（ML）分析，来自莱蒂西亚的Oropouche病毒（OROV）分离株属于谱系2，与在埃斯梅拉达斯获得的样本有着共同的祖先，厄瓜多尔和Turbaco,哥伦比亚。患者：居住在莱蒂西亚市边境地区的一名妇女出现以下症状：发烧，头痛,眶后疼痛和肌痛.
结论：这种跨境监测可用于发出有关该地区虫媒病毒传播的进出的警报，在公共卫生监测系统中经常被低估。
方法：使用多重实时聚合酶链反应（PCR），2019年登革热流行期间的基因测序和临床特征，共分析了175个样本，从通报给系统流行病学监测的病例，如登革热。
结果：根据M和S基因组片段最大似然（ML）分析，来自莱蒂西亚的Oropouche病毒（OROV）分离株属于谱系2，与在埃斯梅拉达斯获得的样本有着共同的祖先，厄瓜多尔和Turbaco,哥伦比亚。患者：居住在莱蒂西亚市边境地区的一名妇女出现以下症状：发烧，头痛,眶后疼痛和肌痛.
结论：这种跨境监测可用于发出有关该地区虫媒病毒传播的进出的警报，在公共卫生监测系统中经常被低估。
