{Reference Type}: Case Reports
{Title}: First case of Oropouche fever detected in the international border region of the Colombian Amazon: clinical characteristics and molecular diagnosis.
{Author}: Grisales-Nieto JC;Luz SLB;Nascimento VAD;Naveca FG;Murcia-Montaño LM;Romero-Vesga KN;Bellido-Cuellar OE;Carvajal-Cortés JJ;
{Journal}: Mem Inst Oswaldo Cruz
{Volume}: 119
{Issue}: 0
{Year}: 2024
{Factor}: 2.747
{DOI}: 10.1590/0074-02760230221
{Abstract}: <B>OBJECTIVE: </B>We report the first case of Oropouche fever detected in the border region of Colombia.<BR><B>METHODS: </B>Using a multiplex real-time polymerase chain reaction (PCR), genetic sequencing and clinical characteristics during the dengue epidemic in 2019, a total of 175 samples were analysed, from cases notified to the system epidemiological surveillance such as dengue.<BR><B>RESULTS: </B>The Oropouche virus (OROV) isolate from Leticia belongs to lineage 2 according to both M and S genome segments maximum likelihood (ML) analysis, shares a common ancestor with samples obtained in Esmeraldas, Ecuador and Turbaco, Colombia. The patient: a woman resident in the border neighbourhood of the municipality of Leticia had the following symptoms: fever, headache, retro-orbital pain and myalgias.<BR><B>CONCLUSIONS: </B>This cross-border surveillance can be useful to give an alert about the entry or exit of arboviruses circulation in the region, which are often underreported in public health surveillance systems.