Abstract：
BACKGROUND: Postpartum hemorrhage (PPH) is a leading cause of maternity mortality in the United States. The Code Crimson project aimed to enhance PPH management by implementing a standardized intervention bundle to mitigate morbidity and mortality associated with PPH.
OBJECTIVE: At a large Philadelphia tertiary hospital, health disparities existed for severe maternal morbidity and mortality, and PPH was a significant factor.
METHODS: A quality improvement design, using Plan-Do-Study-Act cycles and interrupted time series analysis, was undertaken.
METHODS: The Code Crimson project implemented a standardized bundle to manage PPH, including blood product administration and massive transfusion protocol activation.
RESULTS: After implementing the Code Crimson bundle, there was a significant decrease in blood product use ( P < .001), with minor reductions in packed red blood cell administration over 4 units and mean blood loss.
CONCLUSIONS: The Code Crimson bundle effectively reduced blood product utilization for PPH treatment.
OBJECTIVE: At a large Philadelphia tertiary hospital, health disparities existed for severe maternal morbidity and mortality, and PPH was a significant factor.
METHODS: A quality improvement design, using Plan-Do-Study-Act cycles and interrupted time series analysis, was undertaken.
METHODS: The Code Crimson project implemented a standardized bundle to manage PPH, including blood product administration and massive transfusion protocol activation.
RESULTS: After implementing the Code Crimson bundle, there was a significant decrease in blood product use ( P < .001), with minor reductions in packed red blood cell administration over 4 units and mean blood loss.
CONCLUSIONS: The Code Crimson bundle effectively reduced blood product utilization for PPH treatment.
摘要：
背景：产后出血（PPH）是美国产妇死亡的主要原因。CodeCrimson项目旨在通过实施标准化干预措施来改善PPH管理，以减轻与PPH相关的发病率和死亡率。
目标：在费城一家大型三级医院，严重的孕产妇发病率和死亡率存在健康差异，PPH是一个重要因素。
方法：质量改进设计，使用Plan-Do-Study-Act周期和中断的时间序列分析，进行了。
方法：CodeCrimson项目实现了一个标准化捆绑来管理PPH，包括血液制品管理和大量输血方案激活。
结果：在实现CodeCrimson捆绑包之后，血液制品使用量显着下降（P<.001），在4个单位以上的浓缩红细胞给药和平均失血量略有减少。
结论：CodeCrimson束有效降低了PPH治疗的血液制品利用率。
目标：在费城一家大型三级医院，严重的孕产妇发病率和死亡率存在健康差异，PPH是一个重要因素。
方法：质量改进设计，使用Plan-Do-Study-Act周期和中断的时间序列分析，进行了。
方法：CodeCrimson项目实现了一个标准化捆绑来管理PPH，包括血液制品管理和大量输血方案激活。
结果：在实现CodeCrimson捆绑包之后，血液制品使用量显着下降（P<.001），在4个单位以上的浓缩红细胞给药和平均失血量略有减少。
结论：CodeCrimson束有效降低了PPH治疗的血液制品利用率。
