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Abstract：
Primary cardiac lymphoma is an exceedingly rare malignant tumor, with diffuse large B-cell lymphoma (DLBCL) being the most prevalent histological subtype. This disease has non-specific clinical manifestations, making early diagnosis crucial. However, DLBCL diagnosis is commonly delayed, and its prognosis is typically poor. Herein, we report the case of a 51-year-old male patient with DLBCL who presented with recurrent chest tightness for 4 months as the primary clinical symptom. The patient was admitted to the hospital and diagnosed with acute myocardial infarction and left ventricular hypertrophy with heart failure. Echocardiography revealed a progression from left ventricular thickening to local pericardial thickening and adhesion in the inferior and lateral walls of the left ventricle. Finally, pathological analysis of myocardial biopsy confirmed the diagnosis of DLBCL. After treatment with the R-CHOP chemotherapy regimen, the patient\'s chest tightness improved, and he was discharged. After 2 months, the patient succumbed to death owing to sudden ventricular tachycardia, ventricular fibrillation, and decreased blood pressure despite rescue efforts. Transthoracic echocardiography is inevitable for the early diagnosis of DLBCL, as it can narrow the differential and guide further investigations and interventions, thereby improving the survival of these patients.
摘要：
原发性心脏淋巴瘤是一种极为罕见的恶性肿瘤，弥漫性大B细胞淋巴瘤（DLBCL）是最常见的组织学亚型。本病具有非特异性临床表现,使早期诊断至关重要。然而,DLBCL诊断通常延迟，其预后通常较差。在这里，我们报道了一例51岁男性DLBCL患者,以4个月反复发作的胸闷为主要临床症状.患者入院，诊断为急性心肌梗死和左心室肥厚伴心力衰竭。超声心动图显示从左心室增厚到左心室下壁和侧壁的局部心包增厚和粘连。最后,心肌活检病理分析证实了DLBCL的诊断。用R-CHOP化疗方案治疗后，患者的胸闷改善，他出院了.两个月后,病人死于突发性室性心动过速,心室纤颤,尽管有抢救努力，血压还是下降了。经胸超声心动图对DLBCL的早期诊断具有重要意义。因为它可以缩小差异并指导进一步的调查和干预，从而提高这些患者的生存率。
