关键词: Hypokalaemia endocrinology surgical management systemic hypertension

来  源:   DOI:10.1177/20551169241243012   PDF(Pubmed)

Abstract:
UNASSIGNED: A 10-year-old neutered male domestic shorthair cat was presented with an abdominal mass, associated renal failure, chronic vomiting, anorexia and progressive polyuria/polydipsia lasting for 3 weeks. Clinical examination and initial blood work revealed azotaemia, hypokalaemia and hypertension. Abdominal ultrasound showed an adrenal mass with a diameter of 3 cm near the right kidney. High serum aldosterone suggested primary hyperaldosteronism. Surgery enabled identification of the mass and its excision along with the right adrenal gland. Histologically, carcinoma of the adrenal cortex was diagnosed. Postoperatively, an increase in serum creatinine and potassium, along with a low serum aldosterone, led to a diagnosis of hypoaldosteronism. Mineralocorticoid therapy for 6 months was necessary, resulting in clinical and biological improvement.
UNASSIGNED: To our knowledge, this case describes the longest-lasting reported secondary hypoaldosteronism in a cat, after unilateral adrenalectomy for an adrenal carcinoma with hyperaldosteronism.
摘要:
一只10岁绝育的雄性家猫出现腹部肿块,相关的肾功能衰竭,慢性呕吐,厌食症和进行性多尿/多饮持续3周。临床检查和最初的血液检查显示氮血症,低钾血症和高血压。腹部超声显示右肾附近有直径3cm的肾上腺肿块。血清醛固酮升高提示原发性醛固酮增多症。手术可以识别肿块及其切除以及右肾上腺。组织学上,诊断为肾上腺皮质癌。术后,血清肌酐和钾的增加,伴随着低血清醛固酮,导致了醛固酮增多症的诊断.盐皮质激素治疗6个月是必要的,导致临床和生物学改善。
据我们所知,这个病例描述了猫中持续时间最长的继发性醛固酮增多症,伴有醛固酮增多症的肾上腺癌的单侧肾上腺切除术后。
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