UNASSIGNED: This is an elderly patient with multiple injuries caused by falling from a building, and was transferred to intensive care unit (ICU) for mechanical ventilation and empirical anti-infection treatment due to severe pneumonia, and then the results of targeted next-generation sequencing (tNGS) in patient\'s bronchoalveolar lavage fluid (BALF) suggested TW and human metapneumovirus (HMPV) infection, and after switching to anti-infective therapy for TW, the patient was successfully extubated and transferred out of the ICU.
UNASSIGNED: This is the first case of using tNGS to diagnose severe pneumonia caused by TW and HMPV. We hope that our study can serve as a reference for the diagnosis and treatment of related cases in the future.
■这是一名因从建筑物坠落而多处受伤的老年患者,并因重症肺炎转入重症监护病房(ICU)进行机械通气和经验性抗感染治疗,然后患者支气管肺泡灌洗液(BALF)中的靶向下一代测序(tNGS)结果提示TW和人偏肺病毒(HMPV)感染,在改用抗感染治疗TW后,患者成功拔管并转出ICU.
■这是使用tNGS诊断由TW和HMPV引起的严重肺炎的第一例。希望我们的研究能为今后相关病例的诊治提供参考。