PDF(Pubmed)
Abstract：
BACKGROUND: Mirror therapy (MT) has been shown to be effective for motor recovery of the upper limb after a stroke. The cerebral mechanisms of mirror therapy involve the precuneus, premotor cortex and primary motor cortex. Activation of the precuneus could be a marker of this effectiveness. MT has some limitations and video therapy (VT) tools are being developed to optimise MT. While the clinical superiority of these new tools remains to be demonstrated, comparing the cerebral mechanisms of these different modalities will provide a better understanding of the related neuroplasticity mechanisms.
METHODS: Thirty-three right-handed healthy individuals were included in this study. Participants were equipped with a near-infrared spectroscopy headset covering the precuneus, the premotor cortex and the primary motor cortex of each hemisphere. Each participant performed 3 tasks: a MT task (right hand movement and left visual feedback), a VT task (left visual feedback only) and a control task (right hand movement only). Perception of illusion was rated for MT and VT by asking participants to rate the intensity using a visual analogue scale. The aim of this study was to compare brain activation during MT and VT. We also evaluated the correlation between the precuneus activation and the illusion quality of the visual mirrored feedback.
RESULTS: We found a greater activation of the precuneus contralateral to the visual feedback during VT than during MT. We also showed that activation of primary motor cortex and premotor cortex contralateral to visual feedback was more extensive in VT than in MT. Illusion perception was not correlated with precuneus activation.
CONCLUSIONS: VT led to greater activation of a parieto-frontal network than MT. This could result from a greater focus on visual feedback and a reduction in interhemispheric inhibition in VT because of the absence of an associated motor task. These results suggest that VT could promote neuroplasticity mechanisms in people with brain lesions more efficiently than MT.
BACKGROUND: NCT04738851.
METHODS: Thirty-three right-handed healthy individuals were included in this study. Participants were equipped with a near-infrared spectroscopy headset covering the precuneus, the premotor cortex and the primary motor cortex of each hemisphere. Each participant performed 3 tasks: a MT task (right hand movement and left visual feedback), a VT task (left visual feedback only) and a control task (right hand movement only). Perception of illusion was rated for MT and VT by asking participants to rate the intensity using a visual analogue scale. The aim of this study was to compare brain activation during MT and VT. We also evaluated the correlation between the precuneus activation and the illusion quality of the visual mirrored feedback.
RESULTS: We found a greater activation of the precuneus contralateral to the visual feedback during VT than during MT. We also showed that activation of primary motor cortex and premotor cortex contralateral to visual feedback was more extensive in VT than in MT. Illusion perception was not correlated with precuneus activation.
CONCLUSIONS: VT led to greater activation of a parieto-frontal network than MT. This could result from a greater focus on visual feedback and a reduction in interhemispheric inhibition in VT because of the absence of an associated motor task. These results suggest that VT could promote neuroplasticity mechanisms in people with brain lesions more efficiently than MT.
BACKGROUND: NCT04738851.
摘要：
背景：镜像疗法（MT）已被证明对中风后上肢的运动恢复有效。镜像疗法的大脑机制涉及前肌，运动前皮层和初级运动皮层。前突的激活可能是这种有效性的标志。MT有一些局限性，正在开发视频治疗（VT）工具来优化MT。虽然这些新工具的临床优势仍有待证明，比较这些不同模式的脑机制将提供对相关神经可塑性机制的更好理解。
方法：本研究纳入了33例右撇子健康个体。参与者配备了覆盖前突的近红外光谱耳机，每个半球的运动前皮层和初级运动皮层。每个参与者执行3个任务：MT任务（右手移动和左视觉反馈），室性心动过速任务(仅左视觉反馈)和控制任务(仅右手移动)。通过要求参与者使用视觉模拟量表对强度进行评分，对MT和VT的错觉进行评分。这项研究的目的是比较MT和VT期间的大脑激活。我们还评估了前肌激活与视觉镜像反馈的错觉质量之间的相关性。
结果：我们发现，与MT相比，VT过程中视觉反馈对侧的前肌激活更大。我们还表明，与视觉反馈对侧的初级运动皮层和运动前皮层的激活在VT中比在MT中更广泛。错觉感与前肌激活无关。
结论：VT导致比MT更大的顶额叶网络激活。这可能是由于缺乏相关的运动任务而导致对视觉反馈的更多关注以及室性心动过速的半球间抑制减少。这些结果表明，VT可以比MT更有效地促进脑部病变患者的神经可塑性机制。
背景：NCT04738851。
方法：本研究纳入了33例右撇子健康个体。参与者配备了覆盖前突的近红外光谱耳机，每个半球的运动前皮层和初级运动皮层。每个参与者执行3个任务：MT任务（右手移动和左视觉反馈），室性心动过速任务(仅左视觉反馈)和控制任务(仅右手移动)。通过要求参与者使用视觉模拟量表对强度进行评分，对MT和VT的错觉进行评分。这项研究的目的是比较MT和VT期间的大脑激活。我们还评估了前肌激活与视觉镜像反馈的错觉质量之间的相关性。
结果：我们发现，与MT相比，VT过程中视觉反馈对侧的前肌激活更大。我们还表明，与视觉反馈对侧的初级运动皮层和运动前皮层的激活在VT中比在MT中更广泛。错觉感与前肌激活无关。
结论：VT导致比MT更大的顶额叶网络激活。这可能是由于缺乏相关的运动任务而导致对视觉反馈的更多关注以及室性心动过速的半球间抑制减少。这些结果表明，VT可以比MT更有效地促进脑部病变患者的神经可塑性机制。
背景：NCT04738851。
