Abstract：
Cosmetics have been extremely popular throughout history and continue to be so today. Cosmetic and personal care products, including toothpaste, shampoo, lotions, and makeup, are typically made with petroleum-based surfactants. Currently, there is an increasing demand to enhance the sustainability of surface-active compounds in dermal formulations. Biosurfactants, derived from living cells, are considered more environmentally friendly than synthetic surfactants. Thus, the use of biosurfactants is a promising strategy for formulating more environmentally friendly and sustainable dermal products. Biosurfactants have the potential to replace chemical surface-active agents in the cosmetic sector due to their multifunctional qualities, such as foaming, emulsifying, and skin-moisturizing activities.In this study, two glycolipopeptide biosurfactants derived from Lactiplantibacillus plantarum OL5 were used as stabilizing factors in oil-in-water emulsions in the presence of coconut oils. Both biosurfactants increased emulsion stability, particularly in the 1:3 ratio, dispersion, and droplet size. Moreover, the cytotoxicity of the two Lactiplantibacillus plantarum biosurfactants was assessed on B lymphocytes and MCF-7 cells. Overall, the results gathered herein are very promising for the development of new green cosmetic formulations.
摘要：
化妆品在历史上一直非常受欢迎，今天仍然如此。化妆品和个人护理产品，包括牙膏,洗发水,乳液,和化妆，通常用石油基表面活性剂制成。目前,对增强皮肤制剂中表面活性化合物的可持续性的需求日益增加。生物表面活性剂,来源于活细胞，被认为比合成表面活性剂更环保。因此，使用生物表面活性剂是配制更环保和可持续的皮肤产品的有前途的策略。生物表面活性剂由于其多功能特性，有可能取代化妆品领域的化学表面活性剂。如发泡，乳化,和皮肤保湿活动。在这项研究中,在椰子油存在下，两种源自植物乳杆菌OL5的糖脂肽生物表面活性剂被用作水包油乳液中的稳定因子。两种生物表面活性剂都增加了乳液稳定性，特别是在1:3的比例中，色散，和液滴大小。此外，在B淋巴细胞和MCF-7细胞上评估了两种植物乳杆菌生物表面活性剂的细胞毒性。总的来说,本文收集的结果对于开发新的绿色化妆品配方非常有希望。
