Mesh : Child Humans Acute Chest Syndrome / therapy etiology Anemia, Sickle Cell / therapy complications Emergency Service, Hospital Priapism / therapy etiology Stroke / etiology therapy prevention & control

来  源:   DOI:10.1097/PEC.0000000000003159

Abstract:
UNASSIGNED: Sickle cell disease (SCD) is an important topic for emergency medicine audiences because complications of the disease account for a large proportion of hematologic emergencies that are seen in the emergency department each year. Early recognition and aggressive management of emergency complications of SCD can help to reduce the morbidity and mortality associated with this disease. Although the treatment recommendations for some complications of SCD are based on expert opinion, there has been advancement in the understanding of the pathogenesis of the disease and evidence regarding the treatment options available for managing acute complications. This continuing medical education article will provide a summary of the clinical manifestation and management of the most common acute complications of SCD: infection, vaso-occlusive episode, acute chest syndrome, splenic sequestration, stroke, and priapism.
摘要:
镰状细胞病(SCD)是急诊医学受众的重要话题,因为该疾病的并发症在急诊科每年看到的血液学紧急情况中占很大比例。早期识别和积极处理SCD的紧急并发症有助于降低与该疾病相关的发病率和死亡率。虽然一些SCD并发症的治疗建议是基于专家意见,对该疾病发病机制的理解和可用于治疗急性并发症的治疗方案的证据都有了进展.这篇继续医学教育文章将总结SCD最常见的急性并发症的临床表现和管理:感染,血管闭塞发作,急性胸部综合征,脾隔离术,中风,和阴茎异常勃起。
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