PDF(Pubmed)
Abstract：
UNASSIGNED: Skin grafting is a routinely employed technique to cover the skin defect. Though the skin grafts are technically effortless, they are tiresome because of the prolonged duration of hospital stay, labor-intensive, demanding repeated dressings, and also create a second wound. Platelet-rich plasma (PRP) is one that has a higher concentration of platelets than the blood. Alpha granules of the platelets are rich in growth factors.
UNASSIGNED: To assess the effect of PRP on split-thickness skin graft uptake and donor site healing.
UNASSIGNED: In a single-center-based prospective study done from August 2018 to June 2020, 60 patients with acute and chronic wounds were divided into two equal groups. Autologous PRP was applied on the recipient wound bed and donor site in PRP group, and conventional methods like staples/sutures were used to anchor the skin grafts and standard of care of the donor site in a control group.
UNASSIGNED: Instantaneous graft adhesion was observed in all patients of PRP group. The first graft inspection was delayed. Seroma, hematoma, total number of dressings, and duration of stay in hospital were significantly reduced in the PRP group. Donor site pain in the postoperative period was notably reduced in PRP group. PRP also remarkably hastened the donor site healing.
UNASSIGNED: The application of PRP promotes graft take, minimizes complications, enhances donor site wound healing, mitigates donor site pain, and has immense economic benefits due to the reduced number of dressing changes and shorter hospital stay.
UNASSIGNED: To assess the effect of PRP on split-thickness skin graft uptake and donor site healing.
UNASSIGNED: In a single-center-based prospective study done from August 2018 to June 2020, 60 patients with acute and chronic wounds were divided into two equal groups. Autologous PRP was applied on the recipient wound bed and donor site in PRP group, and conventional methods like staples/sutures were used to anchor the skin grafts and standard of care of the donor site in a control group.
UNASSIGNED: Instantaneous graft adhesion was observed in all patients of PRP group. The first graft inspection was delayed. Seroma, hematoma, total number of dressings, and duration of stay in hospital were significantly reduced in the PRP group. Donor site pain in the postoperative period was notably reduced in PRP group. PRP also remarkably hastened the donor site healing.
UNASSIGNED: The application of PRP promotes graft take, minimizes complications, enhances donor site wound healing, mitigates donor site pain, and has immense economic benefits due to the reduced number of dressing changes and shorter hospital stay.
摘要：
■皮肤移植是用于覆盖皮肤缺损的常规技术。虽然皮肤移植在技术上毫不费力，由于住院时间延长，它们令人厌烦，劳动密集型,要求重复敷料，还会造成第二个伤口。富含血小板的血浆(PRP)是具有比血液更高浓度的血小板的血浆。血小板的α颗粒富含生长因子。
■评估PRP对分裂厚度皮肤移植物吸收和供体部位愈合的影响。
■在2018年8月至2020年6月进行的基于单中心的前瞻性研究中，将60例急性和慢性伤口患者分为两组。PRP组将自体PRP应用于受体伤口床和供体部位，在对照组中，使用常规方法如钉/缝线固定皮肤移植物和供体部位的标准护理。
■在所有PRP组患者中均观察到瞬时移植物粘连。第一次移植检查被推迟。血清腺瘤,血肿,敷料总数，PRP组住院时间显著缩短.PRP组术后供区疼痛明显减轻。PRP也显著加速了供体部位的愈合。
■PRP的应用促进了移植，最大限度地减少并发症，增强供体部位伤口愈合，减轻供体部位疼痛，由于减少了换药次数和缩短了住院时间，因此具有巨大的经济效益。
■评估PRP对分裂厚度皮肤移植物吸收和供体部位愈合的影响。
■在2018年8月至2020年6月进行的基于单中心的前瞻性研究中，将60例急性和慢性伤口患者分为两组。PRP组将自体PRP应用于受体伤口床和供体部位，在对照组中，使用常规方法如钉/缝线固定皮肤移植物和供体部位的标准护理。
■在所有PRP组患者中均观察到瞬时移植物粘连。第一次移植检查被推迟。血清腺瘤,血肿,敷料总数，PRP组住院时间显著缩短.PRP组术后供区疼痛明显减轻。PRP也显著加速了供体部位的愈合。
■PRP的应用促进了移植，最大限度地减少并发症，增强供体部位伤口愈合，减轻供体部位疼痛，由于减少了换药次数和缩短了住院时间，因此具有巨大的经济效益。
