Abstract:
Thyrotoxicosis is the clinical condition resulting from an excess of thyroid hormones for any reason. The main causes are Graves-Basedow disease, toxic multinodular goitre and toxic adenoma. The medical treatment to control thyroid function includes antithyroid drugs, beta blockers, iodine solutions, corticosteroids and cholestyramine. Although therapeutic plasma exchange is not generally part of the therapy, it is an alternative as a preliminary stage before the definitive treatment. This procedure makes it possible to eliminate T4, T3, TSI, cytokines and amiodarone. In most cases, more than one cycle is necessary, either daily or every three days, until clinical improvement is observed. The effect on thyrotoxicosis is temporary, with an approximate duration of 24-48h. This approach has been proposed as a safe and effective alternative when the medical treatment is contraindicated or not effective, and when there is multiple organ failure or emergency surgery is required.
摘要:
甲状腺毒症是由于任何原因导致的甲状腺激素过量的临床状况。主要病因是Graves-Basedow病,毒性多结节性甲状腺肿和毒性腺瘤.控制甲状腺功能的药物治疗包括抗甲状腺药物,β受体阻滞剂,碘溶液,皮质类固醇和胆甾胺。虽然治疗性血浆置换通常不是治疗的一部分,这是一个替代方案,作为一个初步阶段之前的确定治疗。此程序可以消除T4,T3,TSI,细胞因子和胺碘酮。在大多数情况下,一个以上的循环是必要的,每天或每三天,直到观察到临床改善。对甲状腺毒症的影响是暂时的,持续时间约为24-48h。当医学治疗禁忌或无效时,这种方法已被建议作为安全有效的替代方法。当有多器官衰竭或需要紧急手术时。