Abstract：
This study investigated the effects of the antidepressant sertraline hydrochloride (Ser-HCI) on rice physiology when combined with arsenic (III) or cadmium. Hydroponic experiments revealed that combined lower concentrations (0.2 and 0.6 mg L-1) of Ser-HCl and As (III) or Cd increased rice biomass and reduced pH and low molecular weight organic acids. The fluorescence intensity was enhanced with Ser-HCl and As-only treatments, with a significant difference (p < 0.05) in the dissolved organic matter index. There was a decrease in endophyte-specific operational taxonomic units, with proteobacteria dominating the rice root endophytes. The addition of Ser-HCl resulted in the Verrucomicrobiota increasing by 6.4 times, which was positively correlated with malic acid and negatively correlated with pH. Functional annotation highlighted alterations in carbohydrate metabolism pathways. This study provides insights into the interactive effects of Ser-HCl on rice when combined with As (III) or Cd, addressing gaps in our understanding of the impact of antidepressants on plant systems.
摘要：
这项研究调查了抗抑郁药舍曲林盐酸盐（Ser-HCl）与砷（III）或镉联合对水稻生理的影响。水培实验表明，较低浓度（0.2和0.6mgL-1）的Ser-HCl和As（III）或Cd会增加水稻生物量，降低pH值和低分子量有机酸。用Ser-HCl和As-only处理增强了荧光强度，溶解性有机质指数差异显著(p<0.05)。内生菌特定的操作分类单位减少，以蛋白质细菌为主的水稻根系内生菌。Ser-HCl的添加导致Verrucomicrobiota增加了6.4倍，与苹果酸呈正相关,与pH呈负相关。功能注释突出了碳水化合物代谢途径的改变。这项研究提供了有关Ser-HCl与As（III）或Cd结合时对水稻的相互作用的见解，解决我们对抗抑郁药对植物系统影响的理解差距。
