PDF(Pubmed)
Abstract：
BACKGROUND: A Bartholin\'s gland abscess is one of the most common infections in women of reproductive age. Although Bartholin\'s gland abscesses have been reported in prepubertal children, they are rarer in prepubertal children than in adults. Herein, we report a case of bilateral Bartholin\'s gland abscesses in a 4-year-old girl with vitamin A deficiency.
METHODS: A 4-year-old girl diagnosed with autism spectrum disorder was admitted to the hospital for close examination and treatment because of persistent fever and malaise. The child was a marked fussy eater and was diagnosed with corneal ulceration and night blindness secondary to vitamin A deficiency. Both of the patient\'s labia were swollen, and a diagnosis of a bilateral Bartholin\'s gland abscess was made using computed tomography. Incisional drainage was performed under general anesthesia. The patient\'s postoperative course was uneventful, and she was discharged from the hospital on day 8 after the surgery. During hospitalization, attempts were made to correct the vitamin deficiency by adding nutritional supplements to the diet. Three months after the surgery, no recurrence of abscesses was noted.
CONCLUSIONS: Decreased immunocompetence and mucosal barrier function due to vitamin A deficiency is thought to be the underlying cause of Bartholin\'s gland abscesses. Although prepubertal Bartholin\'s gland abscesses have been reported, they are rare. To the best of our knowledge, no reports of bilateral Bartholin\'s gland abscesses potentially caused by vitamin A deficiency have been reported. When prepubertal girls present with Bartholin\'s gland abscesses, the presence of immunodeficiency due to vitamin or trace element deficiency should also be considered.
METHODS: A 4-year-old girl diagnosed with autism spectrum disorder was admitted to the hospital for close examination and treatment because of persistent fever and malaise. The child was a marked fussy eater and was diagnosed with corneal ulceration and night blindness secondary to vitamin A deficiency. Both of the patient\'s labia were swollen, and a diagnosis of a bilateral Bartholin\'s gland abscess was made using computed tomography. Incisional drainage was performed under general anesthesia. The patient\'s postoperative course was uneventful, and she was discharged from the hospital on day 8 after the surgery. During hospitalization, attempts were made to correct the vitamin deficiency by adding nutritional supplements to the diet. Three months after the surgery, no recurrence of abscesses was noted.
CONCLUSIONS: Decreased immunocompetence and mucosal barrier function due to vitamin A deficiency is thought to be the underlying cause of Bartholin\'s gland abscesses. Although prepubertal Bartholin\'s gland abscesses have been reported, they are rare. To the best of our knowledge, no reports of bilateral Bartholin\'s gland abscesses potentially caused by vitamin A deficiency have been reported. When prepubertal girls present with Bartholin\'s gland abscesses, the presence of immunodeficiency due to vitamin or trace element deficiency should also be considered.
摘要：
背景：Bartholin腺脓肿是育龄妇女最常见的感染之一。虽然Bartholin的腺脓肿在青春期前的儿童中已经有报道，青春期前儿童比成人更罕见。在这里，我们报告了1例维生素A缺乏的4岁女孩的双侧Bartholin腺脓肿。
方法：一名被诊断为自闭症谱系障碍的4岁女孩因持续发烧和不适而入院接受密切检查和治疗。这个孩子是一个明显的挑食者，被诊断出患有角膜溃疡和继发于维生素A缺乏的夜盲症。病人的阴唇都肿了,使用计算机断层扫描诊断双侧Bartholin腺脓肿。切口引流在全身麻醉下进行。病人的术后过程是顺利的，手术后第8天她出院了.住院期间,尝试通过在饮食中添加营养补充剂来纠正维生素缺乏症。手术三个月后,未发现脓肿复发.
结论：维生素A缺乏导致的免疫功能和粘膜屏障功能下降被认为是Bartholin腺脓肿的根本原因。虽然已经报道了青春期前Bartholin的腺脓肿，他们是罕见的。据我们所知,没有关于可能由维生素A缺乏引起的双侧Bartholin腺脓肿的报道。当青春期前女孩出现Bartholin\'s腺脓肿时，还应考虑由于维生素或微量元素缺乏引起的免疫缺陷。
方法：一名被诊断为自闭症谱系障碍的4岁女孩因持续发烧和不适而入院接受密切检查和治疗。这个孩子是一个明显的挑食者，被诊断出患有角膜溃疡和继发于维生素A缺乏的夜盲症。病人的阴唇都肿了,使用计算机断层扫描诊断双侧Bartholin腺脓肿。切口引流在全身麻醉下进行。病人的术后过程是顺利的，手术后第8天她出院了.住院期间,尝试通过在饮食中添加营养补充剂来纠正维生素缺乏症。手术三个月后,未发现脓肿复发.
结论：维生素A缺乏导致的免疫功能和粘膜屏障功能下降被认为是Bartholin腺脓肿的根本原因。虽然已经报道了青春期前Bartholin的腺脓肿，他们是罕见的。据我们所知,没有关于可能由维生素A缺乏引起的双侧Bartholin腺脓肿的报道。当青春期前女孩出现Bartholin\'s腺脓肿时，还应考虑由于维生素或微量元素缺乏引起的免疫缺陷。
