Abstract：
BACKGROUND: To investigate the relationship between egg consumption and mortality in individuals with pre-existing coronary heart disease or stroke.
METHODS: This study utilized data from the National Health and Nutrition Examination Survey conducted between 1999 and 2018. Egg consumption was evaluated through 24 h dietary recalls at baseline. Mortality status was tracked until December 31, 2019. Survey-weighted Cox proportional hazards models were utilized.
RESULTS: The study involved 3,975 participants aged 20 years or older with a median follow-up of 89.00 months. A total of 1,675 individuals died during follow-up. Compared to individuals who did not consume eggs, the consumption of 0-50 g/day (hazard ratio [HR] = 1.033, 95% confidence interval [CI] =0.878-1.214) was not found to have a significant association with all-cause mortality. However, consuming 50-100 g/day (HR = 1.281, 95% CI = 1.004-1.635) and >100 g/day (HR = 1.312, 95% CI =1.036-1.661) exhibited a significant association with an increased risk of all-cause mortality. We identified a non-liner relationship between egg consumption and cardiovascular mortality, where the risk was found to be lowest at an intake of about 50 g/day. For individuals consuming more than 50 g/day, each additional 50 g increment in egg consumption was significantly linked to an elevated risk of cardiovascular mortality (HR = 1.276, 95% CI = 1.009-1.614).
CONCLUSIONS: In U.S. adults with pre-existing cardiovascular disease, a significant positive association was found between consuming over 50 g of eggs per day and the risk of mortality, highlighting the importance of moderate intake.
METHODS: This study utilized data from the National Health and Nutrition Examination Survey conducted between 1999 and 2018. Egg consumption was evaluated through 24 h dietary recalls at baseline. Mortality status was tracked until December 31, 2019. Survey-weighted Cox proportional hazards models were utilized.
RESULTS: The study involved 3,975 participants aged 20 years or older with a median follow-up of 89.00 months. A total of 1,675 individuals died during follow-up. Compared to individuals who did not consume eggs, the consumption of 0-50 g/day (hazard ratio [HR] = 1.033, 95% confidence interval [CI] =0.878-1.214) was not found to have a significant association with all-cause mortality. However, consuming 50-100 g/day (HR = 1.281, 95% CI = 1.004-1.635) and >100 g/day (HR = 1.312, 95% CI =1.036-1.661) exhibited a significant association with an increased risk of all-cause mortality. We identified a non-liner relationship between egg consumption and cardiovascular mortality, where the risk was found to be lowest at an intake of about 50 g/day. For individuals consuming more than 50 g/day, each additional 50 g increment in egg consumption was significantly linked to an elevated risk of cardiovascular mortality (HR = 1.276, 95% CI = 1.009-1.614).
CONCLUSIONS: In U.S. adults with pre-existing cardiovascular disease, a significant positive association was found between consuming over 50 g of eggs per day and the risk of mortality, highlighting the importance of moderate intake.
摘要：
背景：本研究旨在探讨先前患有冠心病或中风的个体的鸡蛋消耗与死亡率之间的关系。
方法：这项研究利用了1999年至2018年进行的国家健康和营养调查的数据。在基线时通过24小时饮食召回来评估鸡蛋消耗。死亡率状况一直追踪到2019年12月31日。使用调查加权Cox比例风险模型。
结果：该研究涉及3,975名20岁或以上的参与者，中位随访时间为89.00个月。随访期间共有1675人死亡。与不食用鸡蛋的人相比，0~50g/日的消耗量(风险比[HR]=1.033,95%置信区间[CI]=0.878~1.214)未发现与全因死亡率有显著关联.然而,消耗50-100g/天（HR=1.281，95％CI=1.004-1.635）和>100g/天（HR=1.312，95％CI=1.036-1.661）与全因死亡风险增加显著相关。我们确定了鸡蛋消费和心血管死亡率之间的非线性关系，在每天摄入约50克的情况下，风险最低。对于每天摄入超过50克的人，鸡蛋摄入量每增加50g与心血管死亡风险升高显著相关(HR=1.276,95%CI=1.009~1.614).
结论：在美国已有心血管疾病的成年人中，发现每天食用超过50克鸡蛋与死亡风险之间存在显着正相关，强调适度摄入的重要性。
方法：这项研究利用了1999年至2018年进行的国家健康和营养调查的数据。在基线时通过24小时饮食召回来评估鸡蛋消耗。死亡率状况一直追踪到2019年12月31日。使用调查加权Cox比例风险模型。
结果：该研究涉及3,975名20岁或以上的参与者，中位随访时间为89.00个月。随访期间共有1675人死亡。与不食用鸡蛋的人相比，0~50g/日的消耗量(风险比[HR]=1.033,95%置信区间[CI]=0.878~1.214)未发现与全因死亡率有显著关联.然而,消耗50-100g/天（HR=1.281，95％CI=1.004-1.635）和>100g/天（HR=1.312，95％CI=1.036-1.661）与全因死亡风险增加显著相关。我们确定了鸡蛋消费和心血管死亡率之间的非线性关系，在每天摄入约50克的情况下，风险最低。对于每天摄入超过50克的人，鸡蛋摄入量每增加50g与心血管死亡风险升高显著相关(HR=1.276,95%CI=1.009~1.614).
结论：在美国已有心血管疾病的成年人中，发现每天食用超过50克鸡蛋与死亡风险之间存在显着正相关，强调适度摄入的重要性。
