关键词: cryptorchidism orchidopexy puberty spontaneous descent testicular volume

Mesh : Humans Male Cryptorchidism / surgery diagnostic imaging pathology Testis / growth & development diagnostic imaging Adolescent Infant Child Child, Preschool Orchiopexy Puberty / physiology Organ Size Ultrasonography Age Factors Follow-Up Studies

来  源:   DOI:10.1111/apa.17270

Abstract:
OBJECTIVE: To assess testicular volume at puberty for boys who underwent orchidopexy at 9 or at 36 months compared to boys with spontaneous postnatal descent.
METHODS: At age 6 months, boys with congenital unilateral cryptorchidism were randomised to surgery at 9 or 39 months of age and followed to 16 years in parallel with boys with spontaneous postnatal descent. Ultrasound was done at 11 and 16 years to determine testicular volume. The ratio of the initially undescended testis to its scrotal counterpart was used to assess testicular growth.
RESULTS: At age 16, the ratio was lower (p < 0.00) in the late group compared to the early group. At 16 years, the spontaneously descended testes were significantly smaller than their scrotal counterparts but larger than the operated groups (early p < 0.01 and late p < 0.00).
CONCLUSIONS: Our data at 16 years show that orchidopexy at 9 months results in better testicular growth compared to 3 years but did not reach the corresponding volumes of their scrotal counterparts. This indicates that earlier surgery is beneficial to testicular growth. At age 16, the postnatally descended testes were not only larger than the surgically treated testes but also exhibited impaired testicular growth.
摘要:
目的:评估9个月或36个月时接受睾丸固定术的男孩在青春期的睾丸体积,与自然出生后的男孩相比。
方法:6月龄时,患有先天性单侧隐睾的男孩在9个月或39个月大时被随机接受手术治疗,随访至16岁,并与有自然出生后血统的男孩同时接受手术治疗.在11年和16年进行超声检查以确定睾丸体积。最初未下降的睾丸与其阴囊对应物的比率用于评估睾丸生长。
结果:在16岁时,与早期组相比,晚期组的比率较低(p<0.00)。16岁时,自发下降的睾丸明显小于其阴囊对应物,但大于手术组(早期p<0.01和晚期p<0.00)。
结论:我们在16年的数据表明,与3年相比,9个月的睾丸固定术可导致更好的睾丸生长,但未达到相应的阴囊体积。这表明早期手术有利于睾丸生长。16岁时,出生后下降的睾丸不仅比手术治疗的睾丸大,而且睾丸生长受损。
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