PDF(Pubmed)
Abstract：
Early childhood caries (ECC) is a growing public health concern worldwide. Although numerous systematic reviews have been published regarding the association between breastfeeding and early childhood caries (ECC), the results remain inconclusive and equivocal. This systematic review synthesises the evidence on the association between breastfeeding and ECC. Five electronic databases and backward citation chasing were performed from inception until May 2023. A total of 31 studies (22 cohort studies and 9 case-control studies) were included in this review. The meta-analysis of the case-control studies showed statistically significant fewer dental caries in children who were breastfed for < 6 months compared to those who were breastfed for ≥6 months (OR = 0.53, 95% CI 0.41-0.67, p < 0.001). There was a statistically significant difference in dental caries between children who were breastfed for <12 months and those who were breastfed for ≥12 months (RR = 0.65, 95% CI 0.50-0.86, p < 0.002). Similarly, there was a statistically significant difference in dental caries in children who were breastfed for < 18 months compared to those who were breastfed for ≥18 months (RR = 0.41, 95% CI 0.18-0.92, p = 0.030). Nocturnal breastfeeding increases the risk of ECC compared with no nocturnal breastfeeding (RR = 2.35, 95% CI 1.42-3.89, p < 0.001). The findings suggest breastfeeding for more than 12 months and nocturnal breastfeeding increase the risk of ECC.
摘要：
早期儿童龋齿（ECC）是全球范围内日益增长的公共卫生问题。尽管已经发表了许多关于母乳喂养与儿童早期龋齿（ECC）之间关联的系统评价，结果仍然没有定论和模棱两可。本系统综述综合了母乳喂养与ECC之间关联的证据。从成立到2023年5月，进行了五个电子数据库和向后的引文追逐。本综述共纳入31项研究（22项队列研究和9项病例对照研究）。病例对照研究的荟萃分析显示，与母乳喂养≥6个月的儿童相比，母乳喂养<6个月的儿童龋齿发生率显著降低(OR=0.53，95%CI0.41-0.67，p<0.001)。母乳喂养<12个月的儿童与母乳喂养≥12个月的儿童龋齿差异有统计学意义(RR=0.65,95%CI0.50-0.86,p<0.002)。同样，母乳喂养<18个月的儿童与母乳喂养≥18个月的儿童相比,龋齿有统计学差异(RR=0.41,95%CI0.18-0.92,p=0.030).与没有夜间母乳喂养相比，夜间母乳喂养会增加ECC的风险（RR=2.35，95％CI1.42-3.89，p<0.001）。研究结果表明，母乳喂养超过12个月，夜间母乳喂养会增加ECC的风险。
