PDF(Pubmed)
Abstract：
There are a wide range of commercial infant formulae available on the market. These are made using milk from different species, such as goat, sheep, and cow. The different protein compositions of these milks and the process used during infant-formulae manufacture, such as heat treatment, may impact the digestion of nutrients. This study compared the effect of protein composition and heat treatment on the in vitro gastric digestion behaviour of commercial infant formulae made with cow, goat, and sheep milk using a dynamic infant human gastric simulator (IHGS). During the simulated dynamic gastric digestion, the goat milk infant formula (GIF) showed earlier signs of aggregate formation compared to cow milk infant formula (CIF) and sheep milk infant formula (SIF). In addition, the microstructures of GIF chyme showed fragmented and porous structures. On the contrary, CIF formed dense protein networks that trapped oil droplets, whereas SIF exhibited a microstructure of smooth oil droplets surrounded by fewer protein networks. The different aggregation behaviours and aggregate structures of the three infant-formulae chyme were related to their different protein compositions, especially the different casein compositions. Furthermore, the open fragile structure of GIF aggregates provided easier access to pepsin, allowing it to hydrolyse protein. The results from the present study provided some information to assist in understanding the coagulation and digestion behaviours of commercial infant formulae made from different species of milk.
摘要：
市场上有各种各样的商业婴儿配方食品。这些是用不同物种的牛奶制成的，比如山羊,绵羊,和牛。这些牛奶的不同蛋白质组成和婴儿配方食品制造过程中使用的工艺，如热处理，可能会影响营养物质的消化。这项研究比较了蛋白质成分和热处理对牛制成的商业婴儿配方奶粉的体外胃消化行为的影响，山羊,和使用动态婴儿人体胃模拟器（IHGS）的羊奶。在模拟动态胃消化过程中，与牛奶婴儿配方食品（CIF）和羊奶婴儿配方食品（SIF）相比，山羊奶婴儿配方食品（GIF）显示出更早的聚集体形成迹象。此外,GIF食糜的微观结构呈碎片状和多孔结构。相反,CIF形成了密集的蛋白质网络，捕获了油滴，而SIF表现出被较少的蛋白质网络包围的光滑油滴的微观结构。三种婴儿配方食糜的不同聚集行为和聚集结构与其蛋白质组成不同有关,尤其是不同的酪蛋白成分。此外，GIF聚集体的开放脆弱结构提供了更容易获得胃蛋白酶，让它水解蛋白质。本研究的结果提供了一些信息，以帮助理解由不同种类的牛奶制成的商业婴儿配方食品的凝结和消化行为。
