PDF(Pubmed)
Abstract：
Background: Cytomegalovirus (CMV) infection represents a major issue worldwide, since it constitutes the most common viral congenital infection, with a prevalence of 0.58% and 1-5% in developed and developing countries, respectively. According to recent studies, prenatal treatment significantly decreases the risk of vertical CMV transmission, and early intervention may even prevent the termination of pregnancy. This study aimed to investigate the level of awareness of CMV among pregnant patients through a semi-systematic review. Methods: We included all of the original articles investigating knowledge and awareness about CMV infection among pregnant women. Our research included the PubMed database. Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 statement, the Covidence system automatically guided us to screen the titles and/or abstracts, and then full-texts, followed by data extraction from the eligible studies. Results: We screened 764 studies altogether, with 13 studies included in this analysis. Knowledge about the existence of CMV infection risk varied between the articles, ranging from 11.4% in a study performed in Ireland to 60% reported in a study on the French population. Studies analyzing the impact of educational interventions on patients\' knowledge about preventive measures reported significant improvement compared to their level of awareness before the intervention. Conclusions: Patients\' awareness and knowledge about CMV seemed to be generally low or very low during the last decade before the development of effective secondary prevention methods. Educational interventions seem to be effective, and therefore their wide use could be of potential benefit. In the era of available secondary prevention of vertical transmission, it is crucial to concentrate the efforts of different stakeholders to increase the awareness of cCMV among pregnant women.
摘要：
背景：巨细胞病毒（CMV）感染是世界范围内的主要问题，因为它是最常见的病毒先天性感染，发达国家和发展中国家的患病率分别为0.58%和1-5%，分别。根据最近的研究，产前治疗显著降低CMV垂直传播的风险，早期干预甚至可以防止终止妊娠。本研究旨在通过半系统评价来调查孕妇对CMV的认知水平。方法：我们纳入了所有原始文章，调查了孕妇对CMV感染的知识和认识。我们的研究包括PubMed数据库。遵循2020年系统审查和荟萃分析(PRISMA)声明的首选报告项目，Covidence系统自动引导我们筛选标题和/或摘要，然后是全文，然后从符合条件的研究中提取数据。结果：我们共筛选了764项研究，本分析包括13项研究。关于CMV感染风险存在的知识在文章之间有所不同，从在爱尔兰进行的研究中的11.4％到在法国人口研究中报告的60％。分析教育干预对患者预防措施知识的影响的研究报告说，与干预前的意识水平相比，他们有了显着改善。结论：在开发有效的二级预防方法之前的过去十年中，患者对CMV的认识和知识似乎普遍较低或非常低。教育干预似乎是有效的，因此，它们的广泛使用可能会带来潜在的好处。在垂直传播的二级预防可用的时代，集中不同利益相关者的努力以提高孕妇对cCMV的认识至关重要。
