Abstract：
The large use and emission of p-nitrophenol (p-NP) seriously pollute the environment and endanger human health. In this work, a hydrazone-linked fluorescent covalent organic framework (BATHz-COF) was simply synthesized at room temperature and covalently linked N-acetyl-L-cysteine (NALC) via the \"thiol-ene\" click reaction, where carboxyl groups were introduced to improve dispersion and fluorescence intensity. As a rapid, good selectivity and reusability fluorescence sensor, the obtained COF-NALC has been used for quantitative analysis of p-NP predicated on the internal filtering effect (IFE). Under optimal conditions, COF-NALC enabled quantitative detection of p-NP with a linear range of 5-50 μM and the detection limit was 1.46 μM. The application of COF-NALC to the detection of p-NP in river water samples was successful, and the satisfactory recoveries were 98.0%-109.3%. Furthermore, the fluorescent COF paper chips constructed by in situ growth were combined with a smartphone to build a visual platform for the quick and real-time detection of p-NP, providing an excellent illustration for the development of intelligent fluorescence sensing in environmental analysis.
摘要：
对硝基苯酚(p-NP)的大量使用和排放严重污染环境,危害人类健康。在这项工作中,腙连接的荧光共价有机框架（BATHz-COF）在室温下简单合成，并通过“硫醇-烯”点击反应共价连接N-乙酰基-L-半胱氨酸（NALC），其中引入羧基以改善分散和荧光强度。作为一个快速的，良好的选择性和可重用性荧光传感器，获得的COF-NALC已用于基于内部滤波效应（IFE）的p-NP的定量分析。在最优条件下,COF-NALC能够定量检测p-NP，线性范围为5-50μM，检出限为1.46μM。将COF-NALC应用于河水样品中p-NP的检测是成功的,回收率为98.0%～109.3%。此外，通过原位生长构建的荧光COF纸芯片与智能手机相结合，构建了一个快速实时检测p-NP的视觉平台，为环境分析中智能荧光传感的发展提供了很好的例证。
