了解肿瘤抑制新时代 p53 的复杂性。
关键词: MDM2 MDMX apoptosis cancer treatment cell competition cell-cycle arrest ferroptosis genome stability immunity metabolism metastasis p53 p53 mutation p63 p73 senescence stem cell dynamics targeting p53 tumor suppression
Mesh : Humans Tumor Suppressor Protein p53 / metabolism genetics Neoplasms / genetics metabolism pathology Animals Ferroptosis / genetics Signal Transduction Apoptosis Protein Processing, Post-Translational
来 源:
DOI:10.1016/j.ccell.2024.04.009
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