Abstract：
BACKGROUND: Persons with multiple sclerosis (pwMS) frequently suffer from bladder problems that are not identified and managed optimally, reducing quality of life and increasing risk of health consequences.
OBJECTIVE: This study aimed to investigate associations between bladder problems and well-being of pwMS.
METHODS: The study included 1872 pwMS from France, Germany, Italy, and the UK self-reporting on demographics, MS status, bladder problems and management, and well-being. Logistic regression analyses were performed to investigate associations with self-reported well-being.
RESULTS: Population mean age was 51 years and 79 % were women. Among pwMS, 55 % reported bladder problems indicating overactive bladder (OAB), and 40 % reported self-experienced urinary retention. Self-management of bladder problems was reported by 32 %, 33 % were yet to have problem resolution, and 45 % reported a wish to receive bladder management help. Additionally, 35 % of pwMS reported that bladder problem onset preceded awareness of a link to MS. OAB, problem self-management, and urinary complications were significantly associated with lower well-being.
CONCLUSIONS: Bladder problems affect pwMS across disease subtypes and many attempt self-management. Consequently, pwMS with bladder problems are more likely to experience lower well-being, suggesting an unmet need. Raising awareness of the link between bladder problems and well-being could benefit pwMS living with bladder problems.
OBJECTIVE: This study aimed to investigate associations between bladder problems and well-being of pwMS.
METHODS: The study included 1872 pwMS from France, Germany, Italy, and the UK self-reporting on demographics, MS status, bladder problems and management, and well-being. Logistic regression analyses were performed to investigate associations with self-reported well-being.
RESULTS: Population mean age was 51 years and 79 % were women. Among pwMS, 55 % reported bladder problems indicating overactive bladder (OAB), and 40 % reported self-experienced urinary retention. Self-management of bladder problems was reported by 32 %, 33 % were yet to have problem resolution, and 45 % reported a wish to receive bladder management help. Additionally, 35 % of pwMS reported that bladder problem onset preceded awareness of a link to MS. OAB, problem self-management, and urinary complications were significantly associated with lower well-being.
CONCLUSIONS: Bladder problems affect pwMS across disease subtypes and many attempt self-management. Consequently, pwMS with bladder problems are more likely to experience lower well-being, suggesting an unmet need. Raising awareness of the link between bladder problems and well-being could benefit pwMS living with bladder problems.
摘要：
背景：患有多发性硬化症（pwMS）的人经常患有膀胱问题，这些问题没有得到最佳识别和管理，降低生活质量和增加健康后果的风险。
目的：本研究旨在探讨膀胱问题与pwMS健康之间的关系。
方法：该研究包括来自法国的1872pwMS，德国,意大利,以及英国对人口统计的自我报告，MS状态,膀胱问题和管理，和幸福。进行Logistic回归分析以调查与自我报告的幸福感的关联。
结果：人口平均年龄为51岁，79%为女性。在pwMS中，55%报告膀胱问题表明膀胱过度活动症(OAB),40%的人报告有自我经验的尿潴留。32%的人报告了膀胱问题的自我管理，33%的人还没有解决问题，45%的人表示希望接受膀胱管理帮助。此外,35％的pwMS报告说膀胱问题发作先于意识到与MS的联系。OAB,问题自我管理,泌尿系统并发症与较低的幸福感显著相关。
结论：膀胱问题影响跨疾病亚型的pwMS，许多尝试自我管理。因此,有膀胱问题的pwMS更有可能经历较低的幸福感，暗示一个未满足的需求。提高对膀胱问题与健康之间联系的认识可能会使患有膀胱问题的pwMS受益。
目的：本研究旨在探讨膀胱问题与pwMS健康之间的关系。
方法：该研究包括来自法国的1872pwMS，德国,意大利,以及英国对人口统计的自我报告，MS状态,膀胱问题和管理，和幸福。进行Logistic回归分析以调查与自我报告的幸福感的关联。
结果：人口平均年龄为51岁，79%为女性。在pwMS中，55%报告膀胱问题表明膀胱过度活动症(OAB),40%的人报告有自我经验的尿潴留。32%的人报告了膀胱问题的自我管理，33%的人还没有解决问题，45%的人表示希望接受膀胱管理帮助。此外,35％的pwMS报告说膀胱问题发作先于意识到与MS的联系。OAB,问题自我管理,泌尿系统并发症与较低的幸福感显著相关。
结论：膀胱问题影响跨疾病亚型的pwMS，许多尝试自我管理。因此,有膀胱问题的pwMS更有可能经历较低的幸福感，暗示一个未满足的需求。提高对膀胱问题与健康之间联系的认识可能会使患有膀胱问题的pwMS受益。
