METHODS: Three patients with diverse presentations of osteolytic labyrinthitis from two tertiary care academic medical centers.
METHODS: Case series report analyzing the relevant clinical, radiologic, pathologic, and surgical data on our patients with osteolytic labyrinthitis and comparing these index cases to the existing literature.
METHODS: We describe the varying image findings seen in osteolytic labyrinthitis on computed tomography and magnetic resonance imaging. Also, we report successful surgical intervention and hearing rehabilitation with cochlear implantation in patients with osteolytic labyrinthitis.
RESULTS: Our three patients presented with profound sudden sensorineural hearing loss and vertigo consistent with labyrinthitis. None of the three patients had a history of chronic otitis media. Imaging workup revealed varying degrees of erosion to the otic capsule bone demonstrating the spectrum of disease seen in osteolytic labyrinthitis. Although two cases showed osteolytic changes to the semicircular canals and vestibule, the first case revealed frank bony sequestrum within the obliterated labyrinth. The three cases were taken for surgical debridement and cochlear implantation.
CONCLUSIONS: We propose the new term, osteolytic labyrinthitis-previously referred to as labyrinthine sequestrum-to describe the rare spectrum of disease characterized by destruction of the osseous and membranous labyrinth and potential supplantation with bony sequestrum. Cochlear implantation is a viable option in selected patients with osteolytic labyrinthitis.
方法:来自两个三级护理学术医疗中心的三名表现为溶骨性迷路炎的患者。
方法:病例系列报告分析了相关的临床,放射学,病理性,和我们的溶骨性迷路炎患者的手术数据,并将这些指标病例与现有文献进行比较。
方法:我们描述了在计算机断层扫描和磁共振成像上看到的溶骨性迷路炎的不同图像发现。此外,我们报道了溶骨性迷路炎患者人工耳蜗植入术成功的手术干预和听力康复。
结果:我们的3例患者表现为严重的突发性感觉神经性听力损失和与迷路炎一致的眩晕。三名患者均无慢性中耳炎病史。影像学检查显示,耳囊骨受到不同程度的侵蚀,表明在溶骨性迷路炎中看到的疾病谱。尽管有2例显示半规管和前庭的溶骨改变,第一个病例显示在消失的迷宫内的弗兰克骨裂。3例均采取手术清创和人工耳蜗植入术。
结论:我们提出了新的术语,溶骨性迷路炎-以前称为迷路seemstrum-描述了一种罕见的疾病谱,其特征是骨和膜迷路的破坏以及可能被骨seemstrum取代。在选定的溶骨性迷路炎患者中,人工耳蜗植入是可行的选择。