{Reference Type}: Journal Article
{Title}: Cochlear Implantation in Patients With Osteolytic Labyrinthitis: A Case Series.
{Author}: Thedinger WB;Dornhoffer JR;Merlino DJ;Lane JI;Carlson ML;Kircher ML;
{Journal}: Otol Neurotol
{Volume}: 45
{Issue}: 5
{Year}: 2024 Jun 1
{Factor}: 2.619
{DOI}: 10.1097/MAO.0000000000004193
{Abstract}: <B>OBJECTIVE: </B>To describe the rare process of osteolytic labyrinthitis, previously referred to as labyrinthine sequestrum, which involves progressive obliteration of the bony and membranous labyrinth with eventual supplantation with soft tissue and, in some cases, bony sequestrum.<BR><B>METHODS: </B>Three patients with diverse presentations of osteolytic labyrinthitis from two tertiary care academic medical centers.<BR><B>METHODS: </B>Case series report analyzing the relevant clinical, radiologic, pathologic, and surgical data on our patients with osteolytic labyrinthitis and comparing these index cases to the existing literature.<BR><B>METHODS: </B>We describe the varying image findings seen in osteolytic labyrinthitis on computed tomography and magnetic resonance imaging. Also, we report successful surgical intervention and hearing rehabilitation with cochlear implantation in patients with osteolytic labyrinthitis.<BR><B>RESULTS: </B>Our three patients presented with profound sudden sensorineural hearing loss and vertigo consistent with labyrinthitis. None of the three patients had a history of chronic otitis media. Imaging workup revealed varying degrees of erosion to the otic capsule bone demonstrating the spectrum of disease seen in osteolytic labyrinthitis. Although two cases showed osteolytic changes to the semicircular canals and vestibule, the first case revealed frank bony sequestrum within the obliterated labyrinth. The three cases were taken for surgical debridement and cochlear implantation.<BR><B>CONCLUSIONS: </B>We propose the new term, osteolytic labyrinthitis-previously referred to as labyrinthine sequestrum-to describe the rare spectrum of disease characterized by destruction of the osseous and membranous labyrinth and potential supplantation with bony sequestrum. Cochlear implantation is a viable option in selected patients with osteolytic labyrinthitis.