TLR 激动剂结合树突状细胞疫苗在恶性神经胶质瘤中极化干扰素应答 : 一项随机 II 期试验。
Mesh : Humans Dendritic Cells / immunology drug effects Glioma / immunology therapy Female Male Interferons Middle Aged Cancer Vaccines / immunology administration & dosage therapeutic use CD8-Positive T-Lymphocytes / immunology drug effects Poly I-C / administration & dosage pharmacology Adult Toll-Like Receptors / agonists Imidazoles / pharmacology therapeutic use Aged Vaccination Monocytes / immunology drug effects Brain Neoplasms / immunology therapy drug therapy CD4-Positive T-Lymphocytes / immunology drug effects Immunotherapy / methods Toll-Like Receptor Agonists Carboxymethylcellulose Sodium / analogs & derivatives Polylysine / analogs & derivatives
来 源:
DOI:10.1038/s41467-024-48073-y
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