关键词: Anterior chamber Eye Infections

Mesh : Humans Male Middle Aged Keratitis / microbiology diagnosis drug therapy Eye Infections, Fungal / microbiology diagnosis drug therapy Anti-Bacterial Agents / therapeutic use Keratoplasty, Penetrating Chloramphenicol / therapeutic use administration & dosage Eye Infections, Bacterial / microbiology diagnosis drug therapy Corneal Perforation / microbiology diagnosis

来  源:   DOI:10.1136/bcr-2023-258474   PDF(Pubmed)

Abstract:
A middle-aged male patient presented with a central corneal perforation in a deep stromal infiltrate in his left eye. An emergency therapeutic penetrating keratoplasty was performed. Microbiological evaluation of the corneal scraping specimen revealed septate fungal filaments on stains. However, culture reports after 24 hours from the scraping sample and the excised half corneal button showed growth of gram-negative bacilli. This pathogen was identified as an aerobic, non-fermentative, gram-negative, bacillus by conventional microbiology and confirmed as Myroides species by the VITEK 2 Compact system (bioMérieux, Marcy l\'Etoile, France). Susceptibility to chloramphenicol was noted based on which the patient was treated with topical chloramphenicol 0.5%. No recurrence of the infection was noted. This is the first reported case of corneal infection with the Myroides species of bacteria which, heretofore, have been known to cause endocarditis and urinary tract infections.
摘要:
一名中年男性患者在左眼的深层基质浸润中出现中央角膜穿孔。进行了紧急治疗性穿透性角膜移植术。角膜刮擦标本的微生物学评估显示,污渍上有分隔的真菌丝。然而,24小时后从刮擦样品和切除的半角膜纽扣的培养报告显示革兰氏阴性杆菌的生长。这种病原体被鉴定为需氧的,非发酵,革兰氏阴性,杆菌通过常规微生物学,并通过VITEK2Compact系统确认为Myroides物种(bioMérieux,Marcyl\'Etoile,法国)。注意到对氯霉素的易感性,基于该患者用0.5%的局部氯霉素治疗。没有发现感染复发。这是第一例报道的角膜感染的Myroides细菌,到目前为止,已知引起心内膜炎和尿路感染。
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