Abstract：
Social memory, the ability to recognize and remember individuals within a social group, is crucial for social interactions and relationships. Deficits in social memory have been linked to several neuropsychiatric and neurodegenerative disorders. The hippocampus, especially the circuit that links dorsal CA2 and ventral CA1 neurons, is considered a neural substrate for social memory formation. Recent studies have provided compelling evidence of extrahippocampal contributions to social memory. The septal nuclei, including the medial and lateral septum, make up a basal forebrain region that shares bidirectional neuronal connections with the hippocampus and has recently been identified as critical for social memory. The focus of our review is the neural circuit mechanisms that underlie social memory, with a special emphasis on the septum. We also discuss the social memory dysfunction associated with neuropsychiatric and neurodegenerative disorders.
摘要：
社会记忆,识别和记住社会群体中个人的能力，对于社会互动和人际关系至关重要。社会记忆缺陷与几种神经精神和神经退行性疾病有关。海马体,尤其是连接背侧CA2和腹侧CA1神经元的回路，被认为是社会记忆形成的神经基础。最近的研究提供了令人信服的证据，证明海马外对社会记忆的贡献。隔核,包括内侧和外侧隔膜,是一个基底前脑区域，与海马体共享双向神经元连接，最近被认为对社会记忆至关重要。我们回顾的重点是社会记忆背后的神经回路机制，特别强调隔膜。我们进一步讨论了与神经精神和神经退行性疾病相关的社会记忆功能障碍。
