PDF(Pubmed)
Abstract：
OBJECTIVE: Sarcomas of the bone and soft tissues are detected after the onset of pain, detectable mass and related symptoms in the absence of a standardized screening examination. However, primary chest wall sarcomas can be incidentally detected upon chest X-ray or computed tomography. Previous studies of incidental primary chest wall sarcomas lack prognosis and disease-specific clinical data. This study aimed to investigate the prognoses of patients with incidental chest wall sarcomas and compare them with those of symptomatic patients.
METHODS: This study included 18 patients diagnosed with primary chest wall sarcoma between 2010 and 2023. Patient information such as age, sex, tumour diameter, tumour location, symptoms, treatment, time to treatment initiation, pathological diagnosis and outcome were retrospectively analysed.
RESULTS: Among the 18 patients, the sarcomas were incidentally detected in five by chest X-ray and computed tomography in three and two patients, respectively. The pathological diagnoses of the patients were Ewing sarcoma, Chondrosarcoma grade 1, grade 2, periosteal osteosarcoma and malignant peripheral nerve sheath tumour. The patients had no symptoms at the first visit to our hospital, and no lesions in other organs were detected at the time of the initial examination. At the final follow-up, the patients remained disease-free after radical treatment. The tumour sizes of the five patients were significantly smaller than those of patients with symptoms (P = 0.003).
CONCLUSIONS: The incidental detection of chest wall sarcomas and consequent early detection and treatment of tumours improves patient prognosis relative to that of symptomatically diagnosed patients.
METHODS: This study included 18 patients diagnosed with primary chest wall sarcoma between 2010 and 2023. Patient information such as age, sex, tumour diameter, tumour location, symptoms, treatment, time to treatment initiation, pathological diagnosis and outcome were retrospectively analysed.
RESULTS: Among the 18 patients, the sarcomas were incidentally detected in five by chest X-ray and computed tomography in three and two patients, respectively. The pathological diagnoses of the patients were Ewing sarcoma, Chondrosarcoma grade 1, grade 2, periosteal osteosarcoma and malignant peripheral nerve sheath tumour. The patients had no symptoms at the first visit to our hospital, and no lesions in other organs were detected at the time of the initial examination. At the final follow-up, the patients remained disease-free after radical treatment. The tumour sizes of the five patients were significantly smaller than those of patients with symptoms (P = 0.003).
CONCLUSIONS: The incidental detection of chest wall sarcomas and consequent early detection and treatment of tumours improves patient prognosis relative to that of symptomatically diagnosed patients.
摘要：
目的：在疼痛发作后检测到骨和软组织的肉瘤，在没有标准化筛查检查的情况下可检测到的肿块和相关症状。然而,胸部X线或计算机断层扫描可偶然发现原发性胸壁肉瘤。先前对偶然原发性胸壁肉瘤的研究缺乏预后和疾病特异性临床数据。本研究旨在调查偶然发现的胸壁肉瘤患者的预后，并将其与有症状的患者进行比较。
方法：本研究包括2010年至2023年诊断为原发性胸壁肉瘤的18例患者。患者信息，如年龄，性别,肿瘤直径，肿瘤位置,症状,治疗,开始治疗的时间，回顾性分析病理诊断和预后。
结果：在18例患者中，通过胸部X射线和计算机断层扫描在三名和两名患者中偶然发现了5例肉瘤，分别。病理诊断为尤文肉瘤,软骨肉瘤1级，2级，骨膜骨肉瘤和恶性周围神经鞘瘤。病人第一次来我们医院时没有任何症状，初次检查时未发现其他器官的病变。在最后的后续行动中，患者在接受根治性治疗后仍保持无病状态.五名患者的肿瘤大小明显小于有症状的患者（P=0.003）。
结论：胸壁肉瘤的偶然发现和随后的肿瘤的早期发现和治疗相对于有症状诊断的患者，改善了患者的预后。
方法：本研究包括2010年至2023年诊断为原发性胸壁肉瘤的18例患者。患者信息，如年龄，性别,肿瘤直径，肿瘤位置,症状,治疗,开始治疗的时间，回顾性分析病理诊断和预后。
结果：在18例患者中，通过胸部X射线和计算机断层扫描在三名和两名患者中偶然发现了5例肉瘤，分别。病理诊断为尤文肉瘤,软骨肉瘤1级，2级，骨膜骨肉瘤和恶性周围神经鞘瘤。病人第一次来我们医院时没有任何症状，初次检查时未发现其他器官的病变。在最后的后续行动中，患者在接受根治性治疗后仍保持无病状态.五名患者的肿瘤大小明显小于有症状的患者（P=0.003）。
结论：胸壁肉瘤的偶然发现和随后的肿瘤的早期发现和治疗相对于有症状诊断的患者，改善了患者的预后。
