PDF(Pubmed)
Abstract：
There is a lack of robust research investigating the association between neurocognitive impairments and chronic tobacco smoking in adolescents/young adults. Therefore, a systematic review and meta-analysis were conducted to examine this association by pooling cross-sectional studies published from 1980 to 2023. The systematic review assessed the neurocognitive performances between chronic tobacco smokers and non-smokers in each study. The meta-analysis included six studies that compared chronic tobacco smokers against non-smokers using neuropsychological tests covering three neurocognitive domains. The results showed a cross-sectional association between impairpments in motor impulsivity across two aspects: reaction delay and incongruent errors, with the effect size being (SDM = 0.615, p = 0.000) and (SDM = 0.593, p = 0.000) respectively. However, no significant associations were found for intelligence (SDM = 0.221, p = 0.425) or working memory (SDM = 0.150, p = 0.581). This study highlights the need for further research to explore a greater number of neurocognitive domains in the context of chronic smoking in adolescents/young adults, particularly motor impulsivity, intelligence and working memory, as well as the socioeconomic factors involved. There is also a need to further study the effects of emerging alternative nicotine administration methods in this age group.
摘要：
缺乏对青少年/年轻人的神经认知障碍与慢性吸烟之间关系的有力研究。因此,通过汇集1980年至2023年发表的横断面研究,我们进行了系统评价和荟萃分析,以检验这种关联.系统评价评估了每项研究中慢性吸烟者和非吸烟者之间的神经认知表现。荟萃分析包括六项研究，这些研究使用涵盖三个神经认知领域的神经心理学测试将慢性吸烟者与非吸烟者进行了比较。结果表明，运动冲动的损害之间存在两个方面的横截面关联：反应延迟和不一致的错误，效果大小分别为（SDM=0.615，p=0.000）和（SDM=0.593，p=0.000）。然而,没有发现智力(SDM=0.221,p=0.425)或工作记忆(SDM=0.150,p=0.581)显著相关.这项研究强调需要进一步研究，以探索青少年/年轻人慢性吸烟的背景下更多的神经认知领域。尤其是运动冲动，智力和工作记忆，以及所涉及的社会经济因素。还需要进一步研究该年龄组中新兴的替代尼古丁给药方法的效果。
