PDF(Pubmed)
Abstract：
The global burden of diseases and injuries poses complex and pressing challenges. This study analyzed 369 diseases and injuries attributed to 84 risk factors globally from 1990 to 2019, projecting trends to 2040. In 2019, global risks caused 35 million deaths. Non-communicable diseases were responsible for 8.2 million deaths, primarily from air pollution (5.5 million). Cardiovascular disease from air pollution had a high age-standardized disability-adjusted life year rate (1,073.40). Communicable, maternal, neonatal, and nutritional diseases caused 1.4 million deaths, mainly due to unsafe water and sanitation. Occupational risks resulted in 184,269 transport-related deaths. Behavioral risks caused 21.6 million deaths, with dietary factors causing 6.9 million cardiovascular deaths. Diabetes linked to sugar-sweetened beverages showed significant growth (1990-2019). Metabolic risks led to 18.6 million deaths. Projections to 2040 indicated persistent challenges, emphasizing the urgent need for targeted interventions and policies to alleviate the global burden of diseases and injuries.
摘要：
疾病和伤害的全球负担带来了复杂而紧迫的挑战。这项研究分析了1990年至2019年全球由84种危险因素引起的369种疾病和伤害，预测到2040年的趋势。2019年，全球风险造成3500万人死亡。非传染性疾病导致820万人死亡，主要来自空气污染（550万）。空气污染引起的心血管疾病具有较高的年龄标准化残疾调整寿命年率（1,073.40）。可通信,母性,新生儿,营养性疾病导致140万人死亡，主要是由于不安全的水和卫生设施。职业风险导致184,269例与运输有关的死亡。行为风险导致2160万人死亡，饮食因素导致690万人心血管死亡。与含糖饮料相关的糖尿病显着增长（1990-2019年）。代谢风险导致1860万人死亡。到2040年的预测表明持续存在的挑战，强调迫切需要有针对性的干预措施和政策，以减轻全球疾病和伤害负担。
