Abstract：
UNASSIGNED: Optociliary shunt vessels develop as a result of chronic retinal venous obstruction. Optic neuritis has never been reported as a causative influence.
UNASSIGNED: To determine whether optic neuritis predisposes to the development of optociliary shunts in patients with multiple sclerosis.
UNASSIGNED: This case series follows two patients with multiple sclerosis from August 1st, 2019 to April 24th, 2024, who developed optociliary shunt vessels after attacks of optic neuritis. A 43-year-old female presented with left visual loss and bilateral superior optociliary shunt vessels. Perimetry showed bilateral peripheral visual field loss. Optical coherence tomography showed bilateral retinal thinning and ganglion cell complex loss. Optical coherence tomography angiography showed reduced capillary density bilaterally. We investigated her and eventually diagnosed her with multiple sclerosis. The second, a 49-year-old female, developed right-sided optociliary shunt vessels after an episode of neuroretinitis. Perimetry revealed bilateral central scotomata; optical coherence tomography showed disc and retinal nerve fiber layer edema, and serous retinal detachment; later, ganglion cell complex loss; and reduced capillary density on optical coherence tomography angiography. Neuroimaging revealed demyelination in both, leading to a diagnosis of multiple sclerosis, and therapy was instituted.
UNASSIGNED: We hypothesize, that demyelinating optic neuritis due to multiple sclerosis causes chronic retinal hypoperfusion, leading to subsequent optociliary shunt development in affected eyes. Our case series reveals that eyes with optic neuritis, both previous episodes and fresh cases, can contribute to sufficient retinal vein hypoperfusion to cause the development of optociliary shunts, which should be reported in the literature.
Does optic neuritis in multiple sclerosis cause optociliary shunt vessels? Our case study shows that optociliary shunt vessels have developed in eyes having previous as well as fresh optic neuritis in two multiple sclerosis patients, as demonstrated by examination and investigations. We hypothesize that multiple sclerosis causes decreased retinal perfusion predisposing to the development of optociliary shunts. This will guide neurologists and ophthalmologists in diagnosing this debilitating condition upon the visualization of optociliary shunts; heralding previous or recurrent attacks of optic neuritis. @SanaNadeemS.
UNASSIGNED: To determine whether optic neuritis predisposes to the development of optociliary shunts in patients with multiple sclerosis.
UNASSIGNED: This case series follows two patients with multiple sclerosis from August 1st, 2019 to April 24th, 2024, who developed optociliary shunt vessels after attacks of optic neuritis. A 43-year-old female presented with left visual loss and bilateral superior optociliary shunt vessels. Perimetry showed bilateral peripheral visual field loss. Optical coherence tomography showed bilateral retinal thinning and ganglion cell complex loss. Optical coherence tomography angiography showed reduced capillary density bilaterally. We investigated her and eventually diagnosed her with multiple sclerosis. The second, a 49-year-old female, developed right-sided optociliary shunt vessels after an episode of neuroretinitis. Perimetry revealed bilateral central scotomata; optical coherence tomography showed disc and retinal nerve fiber layer edema, and serous retinal detachment; later, ganglion cell complex loss; and reduced capillary density on optical coherence tomography angiography. Neuroimaging revealed demyelination in both, leading to a diagnosis of multiple sclerosis, and therapy was instituted.
UNASSIGNED: We hypothesize, that demyelinating optic neuritis due to multiple sclerosis causes chronic retinal hypoperfusion, leading to subsequent optociliary shunt development in affected eyes. Our case series reveals that eyes with optic neuritis, both previous episodes and fresh cases, can contribute to sufficient retinal vein hypoperfusion to cause the development of optociliary shunts, which should be reported in the literature.
Does optic neuritis in multiple sclerosis cause optociliary shunt vessels? Our case study shows that optociliary shunt vessels have developed in eyes having previous as well as fresh optic neuritis in two multiple sclerosis patients, as demonstrated by examination and investigations. We hypothesize that multiple sclerosis causes decreased retinal perfusion predisposing to the development of optociliary shunts. This will guide neurologists and ophthalmologists in diagnosing this debilitating condition upon the visualization of optociliary shunts; heralding previous or recurrent attacks of optic neuritis. @SanaNadeemS.
摘要：
背景/简介：光纤管分流血管的发展是由于慢性视网膜静脉阻塞。视神经炎从未被报道为致病影响。病例：该病例系列是8月1日以来的两名多发性硬化症患者，2019年4月24日,2024年，在视神经炎发作后出现了光纤毛分流血管。一名43岁的女性，表现为左侧视力丧失和双侧上视纤毛分流血管。视野检查显示双侧周边视野丧失。光学相干断层扫描显示双侧视网膜变薄和神经节细胞复合物丢失。光学相干断层扫描血管造影显示两侧毛细血管密度降低。我们调查了她，最终诊断出她患有多发性硬化症。第二个,49岁女性,神经视网膜炎发作后出现右侧光纤毛分流血管。视野检查显示双侧中央阴囊；光学相干断层扫描显示椎间盘和视网膜神经纤维层水肿，和浆液性视网膜脱离；后来，神经节细胞复合物丢失；光学相干断层扫描血管造影显示毛细血管密度降低。神经影像学显示两者都有脱髓鞘，导致多发性硬化症的诊断，治疗开始了。结论：我们假设，多发性硬化症导致的脱髓鞘视神经炎会导致慢性视网膜灌注不足，导致受影响的眼睛随后发生光纤毛分流。我们的系列病例揭示了患有视神经炎的眼睛，以前的事件和新的案例，可以导致足够的视网膜静脉灌注不足，导致光纤支的发展，这应该在文献中报道。
