PDF(Pubmed)
Abstract：
Xanthomas are well-circumscribed skin lesions that are commonly seen in patients with familial hypercholesterolemia (FH). The aim of this report is to present a rare case of multiple large tuberous and tendinous xanthomas. A 17-year-old female patient in this report presented with multiple asymptomatic and papulo-nodular masses in both sides of palms, elbows, buttocks, knees, and Achilles tendons. Surgical removal of the masses was carried out in combination with lipid-lowering therapy. A following up of 3 months showed all wounds were healing well, and no recurrence of masses was observed. Therefore, for patients with xanthomas related with familial hypercholesterolaemia, lipid-lowering therapy has reportedly reduced the size of masses, but surgical treatment may be essential for large xanthomas caused pain or limitation of daily activities.
摘要：
黄色瘤是明确的皮肤病变，常见于家族性高胆固醇血症（FH）患者。本报告的目的是介绍一例罕见的多发性大结节和腱黄色瘤。本报告中的一名17岁女性患者表现为手掌两侧多发无症状和丘疹结节状肿块，肘部,臀部,膝盖,和跟腱.手术切除肿块与降脂治疗相结合。3个月的随访显示所有伤口愈合良好，没有观察到肿块复发。因此,对于与家族性高胆固醇血症相关的黄色瘤患者，据报道，降脂治疗减少了肿块的大小，但是对于引起疼痛或日常活动受限的大型黄色瘤，手术治疗可能是必不可少的。
