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Abstract：
OBJECTIVE: Obesity, metabolic syndrome, and hyperlipidemia are known as risk factors for colorectal tumors. Colorectal polyps are accepted as potential precursors of colorectal cancer (CRC). This study was designed to clarify the association between the levels of serum lipids and the presence of colorectal polyps.
METHODS: This study was conducted at Basaksehir Cam and Sakura City Hospital, Gastroenterological Surgery Clinic, Istanbul, Turkey. We retrospectively analyzed patients who underwent colonoscopy with serum lipid profile within one month for a one-year period. Groups were analyzed in terms of the correlation between hyperlipidemia and the formation of polyps. The study group was also evaluated in terms of the polyp type, localization, and number.
RESULTS: Among 453 patients, females were 248 and males were 211, with a mean age of 56.7. The study and control groups involved 259 and 194 patients, respectively. The age and serum levels of low-density lipoprotein cholesterol (LDL-C), total cholesterol (TC), and triglyceride (TG) were found to be statistically significant in terms of polyp presence and number (p < 0.05).
CONCLUSIONS: Colorectal polyps are well-known precursors of CRC. We found that the combination of elevated serum levels of low-density lipoprotein cholesterol, total cholesterol, and triglycerides may be a risk predictor for the presence of colorectal polyps, which can be advantageous in cancer screening.
METHODS: This study was conducted at Basaksehir Cam and Sakura City Hospital, Gastroenterological Surgery Clinic, Istanbul, Turkey. We retrospectively analyzed patients who underwent colonoscopy with serum lipid profile within one month for a one-year period. Groups were analyzed in terms of the correlation between hyperlipidemia and the formation of polyps. The study group was also evaluated in terms of the polyp type, localization, and number.
RESULTS: Among 453 patients, females were 248 and males were 211, with a mean age of 56.7. The study and control groups involved 259 and 194 patients, respectively. The age and serum levels of low-density lipoprotein cholesterol (LDL-C), total cholesterol (TC), and triglyceride (TG) were found to be statistically significant in terms of polyp presence and number (p < 0.05).
CONCLUSIONS: Colorectal polyps are well-known precursors of CRC. We found that the combination of elevated serum levels of low-density lipoprotein cholesterol, total cholesterol, and triglycerides may be a risk predictor for the presence of colorectal polyps, which can be advantageous in cancer screening.
摘要：
目标：肥胖，代谢综合征,和高脂血症是结直肠肿瘤的危险因素。结直肠息肉被认为是结直肠癌（CRC）的潜在前体。这项研究旨在阐明血脂水平与结直肠息肉的存在之间的关系。
方法：本研究在BasaksehirCam和SakuraCity医院进行，胃肠病外科诊所,伊斯坦布尔,土耳其。我们回顾性分析了在一个月内接受结肠镜检查的患者的血脂状况，为期一年。对各组进行高脂血症与息肉形成的相关性分析。研究组还根据息肉类型进行了评估，本地化,和数量。
结果：在453名患者中，女性为248，男性为211，平均年龄为56.7。研究组和对照组涉及259和194名患者，分别。低密度脂蛋白胆固醇（LDL-C）的年龄和血清水平，总胆固醇(TC),和甘油三酯（TG）在息肉的存在和数量方面具有统计学意义（p<0.05）。
结论：结直肠息肉是众所周知的CRC前体。我们发现血清低密度脂蛋白胆固醇水平升高，总胆固醇,甘油三酯可能是结肠直肠息肉存在的风险预测因子，这在癌症筛查中可能是有利的。
方法：本研究在BasaksehirCam和SakuraCity医院进行，胃肠病外科诊所,伊斯坦布尔,土耳其。我们回顾性分析了在一个月内接受结肠镜检查的患者的血脂状况，为期一年。对各组进行高脂血症与息肉形成的相关性分析。研究组还根据息肉类型进行了评估，本地化,和数量。
结果：在453名患者中，女性为248，男性为211，平均年龄为56.7。研究组和对照组涉及259和194名患者，分别。低密度脂蛋白胆固醇（LDL-C）的年龄和血清水平，总胆固醇(TC),和甘油三酯（TG）在息肉的存在和数量方面具有统计学意义（p<0.05）。
结论：结直肠息肉是众所周知的CRC前体。我们发现血清低密度脂蛋白胆固醇水平升高，总胆固醇,甘油三酯可能是结肠直肠息肉存在的风险预测因子，这在癌症筛查中可能是有利的。
