Abstract：
Food-borne biotoxins from microbes, plants, or animals contaminate unclean, spoiled, and rotten foods, posing significant health risks. Neutralizing such toxins is vital for human health, especially after food poisoning. Nanobodies (Nbs), a type of single-domain antibodies derived from the genetic cloning of a variable domain of heavy chain antibodies (VHHs) in camels, offer unique advantages in toxin neutralization. Their small size, high stability, and precise binding enable effective neutralization. The use of Nbs in neutralizing food-borne biotoxins offers numerous benefits, and their genetic malleability allows tailored optimization for diverse toxins. As nanotechnology continues to evolve and improve, Nbs are poised to become increasingly efficient and safer tools for toxin neutralization, playing a pivotal role in safeguarding human health and environmental safety. This review not only highlights the efficacy of these agents in neutralizing toxins but also proposes innovative solutions to address their current challenges. It lays a solid foundation for their further development in this crucial field and propels their commercial application, thereby contributing significantly to advancements in this domain.
摘要：
来自微生物的食源性生物毒素，植物,或者动物污染不洁，被宠坏了,腐烂的食物，构成重大健康风险。中和这些毒素对人类健康至关重要，尤其是食物中毒后.纳米体(Nbs),一种单域抗体，来自骆驼重链抗体（VHHs）可变域的遗传克隆，在毒素中和提供独特的优势。他们的小尺寸，高稳定性,和精确的结合使有效的中和。使用Nbs中和食源性生物毒素提供了许多好处，和他们的遗传延展性允许定制优化不同的毒素。随着纳米技术的不断发展和完善，NBS准备成为越来越有效和更安全的毒素中和工具，在保障人类健康和环境安全方面发挥着举足轻重的作用。这篇综述不仅强调了这些药物在中和毒素方面的功效，而且还提出了应对其当前挑战的创新解决方案。它为他们在这一关键领域的进一步发展奠定了坚实的基础，并推动了他们的商业应用，从而对这一领域的进步做出了重大贡献。
