可行性,安全,中非和西非基于 sofosbuvir 的 HCV 治疗的疗效和潜在规模扩大 : ( TAC ANRS 12311 试验 ) 。
关键词: Africa Clinical trial HIV Hepatitis C Sofosvubir Viral resistance
Mesh : Adult Female Humans Male Middle Aged Africa, Central Africa, Western Aminoisobutyric Acids Antiviral Agents / therapeutic use adverse effects Benzimidazoles / therapeutic use adverse effects Benzopyrans Carbamates / therapeutic use Cyclopropanes / therapeutic use adverse effects Drug Therapy, Combination Feasibility Studies Fluorenes / therapeutic use adverse effects Genotype Hepacivirus / genetics drug effects Hepatitis C / drug therapy Hepatitis C, Chronic / drug therapy virology Heterocyclic Compounds, 4 or More Rings / therapeutic use adverse effects Lactams, Macrocyclic Leucine / analogs & derivatives Proline / analogs & derivatives therapeutic use Quinoxalines Ribavirin / therapeutic use adverse effects Sofosbuvir / therapeutic use adverse effects Sulfonamides / therapeutic use adverse effects Sustained Virologic Response Treatment Outcome
来 源:
DOI:10.1038/s41598-024-57013-1
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