Abstract：
UNASSIGNED: Urinary tract infections (UTIs) are a prevalent health challenge characterized by the invasion and multiplication of microorganisms in the urinary system. The continuous exploration of novel therapeutic interventions is imperative. Advances in research offer hope for revolutionizing the management of UTIs and improving the overall health outcomes for individuals affected by these infections.
UNASSIGNED: This review aimed to provide an overview of existing treatments for UTIs, highlighting their strengths and limitations. Moreover, we explored and analyzed the latest therapeutic modalities under clinical development. Finally, the review offered a picture into the potential implications of these therapies on the future landscape of UTIs treatment, discussing possible advancements and challenges for further research.
UNASSIGNED: Comprehensions into the pathogenesis of UTIs have been gleaned from foundational basic science studies, laying the groundwork for the exploration of novel therapeutic interventions. The primary source of evidence originates predominantly from animal studies conducted on murine models. Nevertheless, the lack of clinical trials interferes the acquisition of robust evidence in humans. The challenges presented by the heterogeneity and virulence of uropathogens add an additional layer of complexity, posing an obstacle that scientists and clinicians are actively grappling with in their pursuit of effective solutions.
UNASSIGNED: This review aimed to provide an overview of existing treatments for UTIs, highlighting their strengths and limitations. Moreover, we explored and analyzed the latest therapeutic modalities under clinical development. Finally, the review offered a picture into the potential implications of these therapies on the future landscape of UTIs treatment, discussing possible advancements and challenges for further research.
UNASSIGNED: Comprehensions into the pathogenesis of UTIs have been gleaned from foundational basic science studies, laying the groundwork for the exploration of novel therapeutic interventions. The primary source of evidence originates predominantly from animal studies conducted on murine models. Nevertheless, the lack of clinical trials interferes the acquisition of robust evidence in humans. The challenges presented by the heterogeneity and virulence of uropathogens add an additional layer of complexity, posing an obstacle that scientists and clinicians are actively grappling with in their pursuit of effective solutions.
摘要：
■尿路感染（UTI）是一种普遍的健康挑战，其特征在于泌尿系统中微生物的入侵和繁殖。不断探索新的治疗干预措施势在必行。研究的进展为彻底改变UTI的管理和改善受这些感染影响的个体的整体健康结果提供了希望。
■这篇综述旨在概述尿路感染的现有治疗方法，强调他们的优势和局限性。此外，我们探索并分析了临床开发中的最新治疗方式。最后,该评论提供了一幅图景，这些疗法对UTIs治疗的未来前景的潜在影响，讨论进一步研究可能的进步和挑战。
■从基础基础科学研究中收集了对UTI发病机理的理解，为探索新的治疗干预措施奠定基础。证据的主要来源主要来自在小鼠模型上进行的动物研究。然而，缺乏临床试验妨碍了人类获得强有力的证据。尿路病原体的异质性和毒力带来的挑战增加了额外的复杂性，构成了科学家和临床医生在寻求有效解决方案时积极应对的障碍。
■这篇综述旨在概述尿路感染的现有治疗方法，强调他们的优势和局限性。此外，我们探索并分析了临床开发中的最新治疗方式。最后,该评论提供了一幅图景，这些疗法对UTIs治疗的未来前景的潜在影响，讨论进一步研究可能的进步和挑战。
■从基础基础科学研究中收集了对UTI发病机理的理解，为探索新的治疗干预措施奠定基础。证据的主要来源主要来自在小鼠模型上进行的动物研究。然而，缺乏临床试验妨碍了人类获得强有力的证据。尿路病原体的异质性和毒力带来的挑战增加了额外的复杂性，构成了科学家和临床医生在寻求有效解决方案时积极应对的障碍。
