关键词: Alzheimer’s disease Posterior cortical atrophy visual imagery visuoperceptual visuospatial

Mesh : Humans Male Female Atrophy / pathology Aged Imagination / physiology Middle Aged Cerebral Cortex / diagnostic imaging pathology physiopathology Neuropsychological Tests Agnosia / physiopathology etiology Pattern Recognition, Visual / physiology Visual Perception / physiology Magnetic Resonance Imaging Perceptual Disorders / etiology physiopathology diagnostic imaging

来  源:   DOI:10.1080/02643294.2024.2346362

Abstract:
Visual imagery has a close overlapping relationship with visual perception. Posterior cortical atrophy (PCA) is a neurodegenerative syndrome marked by early impairments in visuospatial processing and visual object recognition. We asked whether PCA would therefore also be marked by deficits in visual imagery, tested using objective forced-choice questionnaires, and whether imagery deficits would be selective for certain properties. We recruited four patients with PCA and a patient with integrative visual agnosia due to bilateral occipitotemporal strokes for comparison. We administered a test battery probing imagery for object shape, size, colour lightness, hue, upper-case letters, lower-case letters, word shape, letter construction, and faces. All subjects showed significant impairments in visual imagery, with imagery for lower-case letters most likely to be spared. We conclude that PCA subjects can show severe deficits in visual imagery. Further work is needed to establish how frequently this occurs and how early it can be found.
摘要:
视觉意象与视觉感知有着密切的重叠关系。后皮质萎缩(PCA)是一种神经退行性综合征,其特征是视觉空间处理和视觉对象识别中的早期损伤。我们询问PCA是否因此也会以视觉图像的缺陷为标志,使用客观的强迫选择问卷进行测试,以及图像缺陷是否会对某些属性有选择性。我们招募了四名PCA患者和一名因双侧枕颞部中风而患有综合视觉失认症的患者进行比较。我们管理了一个测试电池探测物体形状的图像,尺寸,颜色亮度,色调,大写字母,小写字母,单词形状,信建设,和面孔。所有受试者在视觉图像上都表现出明显的障碍,小写字母的图像最有可能幸免。我们得出的结论是,PCA受试者可能在视觉图像上表现出严重的缺陷。需要进一步的工作来确定这种情况发生的频率以及可以在多早发现。
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