关键词: Adherence Epilepsy Intervention Pharmacy Seizures

Mesh : Humans Epilepsy / drug therapy psychology Medication Adherence / statistics & numerical data psychology Pharmacists / psychology Professional Role Anticonvulsants / therapeutic use Patient Education as Topic / methods

来  源:   DOI:10.3961/jpmph.23.592   PDF(Pubmed)

Abstract:
OBJECTIVE: Epilepsy is a chronic disease that requires long-term treatment and intervention from health workers. Medication adherence is a factor that influences the success of therapy for patients with epilepsy. Therefore, this study aimed to analyze the role of pharmacists in improving the clinical outcomes of epilepsy patients, focusing on medication adherence.
METHODS: A scoping literature search was conducted through the ScienceDirect, PubMed, and Google Scholar databases. The literature search included all original articles published in English until August 2023 for which the full text was available. This scoping review was carried out by a team consisting of pharmacists and neurologists following the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) Extension for Scoping Reviews and the Joanna Briggs Institute guidelines, including 5 steps: identifying research questions, finding relevant articles, selecting articles, presenting data, and compiling the results.
RESULTS: The literature search yielded 10 studies that discussed pharmacist interventions for patients with epilepsy. Five articles described educational interventions involving drug-related counseling with pharmacists. Two articles focused on similar pharmacist interventions through patient education, both verbal and written. Three articles discussed an epilepsy review service, a multidisciplinary intervention program involving pharmacists and other health workers, and a mixed intervention combining education and training with therapy-based behavioral interventions.
CONCLUSIONS: Pharmacist interventions have been shown to be effective in improving medication adherence in patients with epilepsy. Furthermore, these interventions play a crucial role in improving other therapeutic outcomes, including patients\' knowledge of self-management, perceptions of illness, the efficacy of antiepileptic drugs in controlling seizures, and overall quality of life.
摘要:
癫痫是一种慢性疾病,需要卫生工作者的长期治疗和干预。药物依从性是影响癫痫患者治疗成功的因素。因此,本研究旨在分析药师在改善癫痫患者临床预后中的作用,专注于药物依从性。
通过ScienceDirect进行了范围界定文献检索,PubMed,和谷歌学者数据库。文献检索包括直到2023年8月以英文发表的所有原始文章,全文可用。这项范围审查是由药剂师和神经学家组成的团队根据PRISMA扩展范围审查和JoannaBriggs研究所指南进行的。包括5个步骤:确定研究问题,查找相关文章,选择文章,呈现数据,并编译结果。
文献检索产生了10项研究,讨论了药剂师对癫痫患者的干预措施。五篇文章描述了与药剂师进行药物相关咨询的教育干预措施。两篇文章侧重于通过患者教育进行类似的药剂师干预,口头和书面。三篇文章讨论了癫痫检查服务,涉及药剂师和其他卫生工作者的多学科干预计划,以及将教育和培训与基于治疗的行为干预相结合的混合干预。
药剂师干预已被证明可有效改善癫痫患者的用药依从性。此外,这些干预措施在改善其他治疗结果中起着至关重要的作用,包括患者的自我管理知识,对疾病的看法,抗癫痫药物控制癫痫发作的疗效,和整体生活质量。
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