Abstract：
Music and ketamine are both known to affect therapeutic outcomes, but few studies have investigated their co-administration. This scoping review describes the existing literature on the joint use of music and ketamine-or esketamine (the S(+) enantiomer of ketamine)-in humans. The review considers that extant studies have explored the intersection of ketamine/esketamine and music in healthy volunteers and in patients of various age groups, at different dosages, through different treatment processes, and have varied the sequence of playing music relative to ketamine/esketamine administration. Studies investigating the use of music during ketamine anesthesia are also included in the review because anesthesia and sedation were the early drivers of ketamine use. Studies pertaining to recreational ketamine use were omitted. The review was limited to articles published in the English language but not restricted by publication year. To the best of our knowledge, this scoping review is the first comprehensive exploration of the interplay between music and ketamine/esketamine and offers valuable insights to researchers interested in designing future studies.
摘要：
众所周知，音乐和氯胺酮都会影响治疗效果，但很少有研究调查他们的共同管理。此范围综述描述了有关音乐和氯胺酮或氯胺酮（氯胺酮的S（）对映体）在人类中联合使用的现有文献。该评论认为，现有研究已经探索了氯胺酮/艾氯胺酮与音乐在健康志愿者和不同年龄段患者中的交集，在不同的剂量，通过不同的处理过程，并且相对于氯胺酮/艾氯胺酮给药改变了播放音乐的顺序。该综述还包括研究氯胺酮麻醉期间音乐的使用，因为麻醉和镇静是氯胺酮使用的早期驱动因素。省略了与娱乐性氯胺酮使用有关的研究。该评论仅限于以英语发表的文章，但不受出版年份的限制。据我们所知,这项范围审查是对音乐与氯胺酮/艾氯胺酮之间相互作用的首次全面探索，并为有兴趣设计未来研究的研究人员提供了有价值的见解。
