METHODS: The PubMed, Web of Science, Embase, Cochrane Library, China National Knowledge Infrastructure (CNKI), Wanfang Database, China Biology Medicine Disc (CBM), and VIP Databases will be comprehensively searched up to May 31, 2024. Randomized controlled trials (RCTs) examining the application of CGF after mandibular third molar extraction will be included. The protocol was registered in PROSPERO, and the registration ID was CRD42023463234. Two reviewers will conduct the literature search, eligible study selection, data extraction, and bias risk assessment (using the Cochrane Risk of Bias 2.0 tool). Data analysis will be performed with RevMan software (version 5.4).
RESULTS: The results of this study will be available in a peer-reviewed journal.
CONCLUSIONS: Our study will provide scientific evidence regarding the efficacy of applying CGF in mandibular third molar extraction.
方法:PubMed,WebofScience,Embase,科克伦图书馆,中国国家知识基础设施(CNKI),万方数据库,中国生物医学光盘(CBM),和VIP数据库将在2024年5月31日之前进行全面搜索。将包括检查下颌第三磨牙拔除后CGF应用的随机对照试验(RCT)。协议在PROSPERO注册,注册ID为CRD42023463234。两名审稿人将进行文献检索,符合条件的研究选择,数据提取,和偏差风险评估(使用Cochrane偏差风险2.0工具)。数据分析将使用RevMan软件(版本5.4)进行。
结果:这项研究的结果将在同行评审的期刊上提供。
结论:我们的研究将为下颌第三磨牙拔除术中应用CGF的疗效提供科学依据。