Abstract：
Secondary malignancies are rare but devastating complications of longstanding burn scars. Squamous cell carcinoma is the most common, followed by basal cell carcinoma and melanomas. There are fewer than 50 total reported cases of malignant melanomas arising in burn scars. We report a case of malignant melanoma arising within a longstanding burn scar confirmed by histology, FISH, and PRAME staining to further characterize melanomas arising in burn scars and to illustrate the diagnostic challenges they present.
摘要：
继发性恶性肿瘤是长期烧伤疤痕的罕见但破坏性的并发症。鳞状细胞癌是最常见的，其次是基底细胞癌和黑色素瘤。在烧伤疤痕中出现的恶性黑色素瘤报告总数不到50例。我们报告了一例恶性黑色素瘤，该黑色素瘤在组织学证实的长期烧伤疤痕中出现，FISH,和PRAME染色，以进一步表征烧伤疤痕中出现的黑素瘤，并说明它们存在的诊断挑战。
