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Abstract：
UNASSIGNED: Colonoscopy is widely used as a tool for diagnosis, screening and treatment of various pathologies in the rectum, colon, and terminal ileum. The aim of this study is to evaluate the demographic, clinical, and histological parameters of the records of patients undergoing colonoscopy at a tertiary care hospital in Nepal.
UNASSIGNED: This retrospective cross-sectional study included the hospital records of all patients who underwent colonoscopy from 2015 to 2019 in a tertiary care centre in Nepal.
UNASSIGNED: A total of 1255 records were included in the study. The mean and standard deviation of age were 43.8 and 19 years, respectively. Among the total study population, 61.9% were males and 38.1% were females. Common indications for colonoscopy included lower gastrointestinal bleeding (27.7%), altered bowel habit (26.9%) and persistent or recurrent abdominal pain (17.3%). Only 3% of the patients who underwent colonoscopy had inadequate bowel preparation. The overall diagnostic yield of colonoscopy was 57.5%. Findings during colonoscopy included colorectal polyp (19.4%), internal haemorrhoids (8.2%) and colitis (6.5%). Having an age of 50 or more years was significantly associated with the presence of colorectal adenocarcinoma (P=0.017, χ2 test) with an odds ratio of 2.35 (95% CI: 1.14, 4.89). Furthermore, having a female sex was found to be significantly associated with the presence of colorectal adenocarcinoma (P=0.012, χ2 test) with an odds ratio of 2.43 (95% CI: 1.19, 4.97).
UNASSIGNED: In the authors\' study, a smaller proportion of the colonoscopies was aimed at screening for colorectal carcinoma (CRC), when compared to studies in developed countries. The sex predisposition of CRC in the authors\' study is in contrast to the global trend. The authors recommend conducting studies to determine the risk factors and need for CRC screening in the Nepalese population.
UNASSIGNED: This retrospective cross-sectional study included the hospital records of all patients who underwent colonoscopy from 2015 to 2019 in a tertiary care centre in Nepal.
UNASSIGNED: A total of 1255 records were included in the study. The mean and standard deviation of age were 43.8 and 19 years, respectively. Among the total study population, 61.9% were males and 38.1% were females. Common indications for colonoscopy included lower gastrointestinal bleeding (27.7%), altered bowel habit (26.9%) and persistent or recurrent abdominal pain (17.3%). Only 3% of the patients who underwent colonoscopy had inadequate bowel preparation. The overall diagnostic yield of colonoscopy was 57.5%. Findings during colonoscopy included colorectal polyp (19.4%), internal haemorrhoids (8.2%) and colitis (6.5%). Having an age of 50 or more years was significantly associated with the presence of colorectal adenocarcinoma (P=0.017, χ2 test) with an odds ratio of 2.35 (95% CI: 1.14, 4.89). Furthermore, having a female sex was found to be significantly associated with the presence of colorectal adenocarcinoma (P=0.012, χ2 test) with an odds ratio of 2.43 (95% CI: 1.19, 4.97).
UNASSIGNED: In the authors\' study, a smaller proportion of the colonoscopies was aimed at screening for colorectal carcinoma (CRC), when compared to studies in developed countries. The sex predisposition of CRC in the authors\' study is in contrast to the global trend. The authors recommend conducting studies to determine the risk factors and need for CRC screening in the Nepalese population.
摘要：
■结肠镜检查被广泛用作诊断工具，直肠各种病理的筛查和治疗，结肠,和回肠末端。这项研究的目的是评估人口统计学，临床,以及在尼泊尔一家三级医院接受结肠镜检查的患者记录的组织学参数。
这项回顾性横断面研究包括2015年至2019年在尼泊尔三级护理中心接受结肠镜检查的所有患者的医院记录。
■本研究共纳入1255条记录。年龄的平均值和标准差分别为43.8和19岁，分别。在整个研究人群中,61.9%为男性，38.1%为女性。结肠镜检查的常见指征包括下消化道出血（27.7%），排便习惯改变(26.9%)和持续性或复发性腹痛(17.3%)。接受结肠镜检查的患者中只有3％的肠道准备不足。结肠镜检查的总诊断率为57.5%。结肠镜检查期间的发现包括结直肠息肉（19.4%），内痔（8.2%）和结肠炎（6.5%）。年龄在50岁或以上与结直肠腺癌的存在显着相关（P=0.017，χ2检验），比值比为2.35（95％CI：1.14，4.89）。此外，发现女性与结直肠腺癌的存在显著相关(P=0.012,χ2检验),比值比为2.43(95%CI:1.19,4.97).
■在作者\'研究中，较小比例的结肠镜检查旨在筛查结直肠癌（CRC），与发达国家的研究相比。作者研究中CRC的性别倾向与全球趋势相反。作者建议开展研究，以确定尼泊尔人群中CRC筛查的危险因素和必要性。
这项回顾性横断面研究包括2015年至2019年在尼泊尔三级护理中心接受结肠镜检查的所有患者的医院记录。
■本研究共纳入1255条记录。年龄的平均值和标准差分别为43.8和19岁，分别。在整个研究人群中,61.9%为男性，38.1%为女性。结肠镜检查的常见指征包括下消化道出血（27.7%），排便习惯改变(26.9%)和持续性或复发性腹痛(17.3%)。接受结肠镜检查的患者中只有3％的肠道准备不足。结肠镜检查的总诊断率为57.5%。结肠镜检查期间的发现包括结直肠息肉（19.4%），内痔（8.2%）和结肠炎（6.5%）。年龄在50岁或以上与结直肠腺癌的存在显着相关（P=0.017，χ2检验），比值比为2.35（95％CI：1.14，4.89）。此外，发现女性与结直肠腺癌的存在显著相关(P=0.012,χ2检验),比值比为2.43(95%CI:1.19,4.97).
■在作者\'研究中，较小比例的结肠镜检查旨在筛查结直肠癌（CRC），与发达国家的研究相比。作者研究中CRC的性别倾向与全球趋势相反。作者建议开展研究，以确定尼泊尔人群中CRC筛查的危险因素和必要性。
