Abstract：
BACKGROUND: Muscular strength and muscle mass are considered key factors for healthy ageing. Modification of body composition and redistribution of adipose tissue has been described in advanced age. Muscle strength has an important predictive role for health outcomes. However, little is known regarding the relationship between muscle strength and epicardial fat.
METHODS: In a cohort of healthy adults following physical capacity evaluations, anthropometric measurements, handgrip strength (HGS), echocardiography and bioimpedance analysis (BIA) were performed. Kruskal-Wallis test, Spearman\'s correlation and regression analysis adjusted for confounders were applied.
RESULTS: A total population of 226 adults, age range 18-83 years, were included. Epicardial fat thickness resulted significantly associated with age p < 0.001, HGS (p < 0.001). Regression analysis adjusted for confounders revealed an independent relationship between handgrip strength and epicardial fat thickness: regression coefficient: -1.34; R2 = 0.27 and p = 0.044.
CONCLUSIONS: The relationship between epicardial fat and muscle strength is inverse and independent. Implementation of HGS measurement may be useful for the identification of subjects with excessive epicardial fat and cardiovascular risk. Measurement of epicardial fat could be helpful in the early detection of physical decline associated to ageing.
METHODS: In a cohort of healthy adults following physical capacity evaluations, anthropometric measurements, handgrip strength (HGS), echocardiography and bioimpedance analysis (BIA) were performed. Kruskal-Wallis test, Spearman\'s correlation and regression analysis adjusted for confounders were applied.
RESULTS: A total population of 226 adults, age range 18-83 years, were included. Epicardial fat thickness resulted significantly associated with age p < 0.001, HGS (p < 0.001). Regression analysis adjusted for confounders revealed an independent relationship between handgrip strength and epicardial fat thickness: regression coefficient: -1.34; R2 = 0.27 and p = 0.044.
CONCLUSIONS: The relationship between epicardial fat and muscle strength is inverse and independent. Implementation of HGS measurement may be useful for the identification of subjects with excessive epicardial fat and cardiovascular risk. Measurement of epicardial fat could be helpful in the early detection of physical decline associated to ageing.
摘要：
背景：肌肉力量和肌肉质量被认为是健康衰老的关键因素。身体成分的改变和脂肪组织的重新分布已经在高龄中被描述。肌肉力量对健康结果具有重要的预测作用。然而,关于肌肉力量和心外膜脂肪之间的关系知之甚少。
方法：在一组健康成年人的身体能力评估后，人体测量,手握强度(HGS),进行超声心动图和生物阻抗分析（BIA）。Kruskal-Wallis测试,采用Spearman相关和校正混杂因素的回归分析。
结果：共有226名成年人，年龄范围18-83岁，包括在内。心外膜脂肪厚度与年龄显著相关，p<0.001，HGS(p<0.001)。校正混杂因素的回归分析显示，握力与心外膜脂肪厚度之间存在独立关系：回归系数：-1.34；R2=0.27，p=0.044。
结论：心外膜脂肪与肌肉力量之间的关系是相反且独立的。HGS测量的实施对于识别具有过多心外膜脂肪和心血管风险的受试者可能是有用的。心外膜脂肪的测量可能有助于早期发现与衰老相关的身体衰退。
方法：在一组健康成年人的身体能力评估后，人体测量,手握强度(HGS),进行超声心动图和生物阻抗分析（BIA）。Kruskal-Wallis测试,采用Spearman相关和校正混杂因素的回归分析。
结果：共有226名成年人，年龄范围18-83岁，包括在内。心外膜脂肪厚度与年龄显著相关，p<0.001，HGS(p<0.001)。校正混杂因素的回归分析显示，握力与心外膜脂肪厚度之间存在独立关系：回归系数：-1.34；R2=0.27，p=0.044。
结论：心外膜脂肪与肌肉力量之间的关系是相反且独立的。HGS测量的实施对于识别具有过多心外膜脂肪和心血管风险的受试者可能是有用的。心外膜脂肪的测量可能有助于早期发现与衰老相关的身体衰退。
