Abstract:
This report describes a 48-year-old man who presented with a month history of weakness and paraesthesia associated with severe pain of all four limbs. Initially diagnosed and treated as Guillain Barre syndrome due to the severity of his extremity weakness, it was later discovered to be eosinophilic granulomatous polyangiitis (EGPA). Mononeuritis multiplex should not be underestimated or overlooked in the setting of diagnosing EGPA and requires prompt treatment with biologics to limit the permanent consequences on patient\'s quality of life with regard to developing limb weakness and pain. Although peripheral neuropathy, namely, mononeuritis multiplex, is not the most common feature of EGPA, it is important to consider it in order not to delay treatment with biologic agents that as seen in our patient can both halt the progress of the disease as well as give the patient a better quality of life.
摘要:
该报告描述了一名48岁的男子,他有一个月的虚弱和感觉异常病史,并伴有所有四肢的剧烈疼痛。最初诊断和治疗为格林巴利综合征,由于他的四肢无力的严重程度,后来发现为嗜酸性肉芽肿性多血管炎(EGPA).在诊断EGPA时,不应低估或忽视多发性单神经炎,并且需要迅速使用生物制剂进行治疗,以限制患者在肢体无力和疼痛方面对生活质量的永久性后果。虽然周围神经病变,即,多发性单神经炎,不是EGPA最常见的特征,重要的是要考虑这一点,以免延迟生物制剂的治疗,正如我们患者所看到的那样,生物制剂既可以阻止疾病的进展,也可以给患者带来更好的生活质量。