PDF(Pubmed)
Abstract：
UNASSIGNED: Attentional bias to reward-associated stimuli can occur even when it interferes with goal-driven behavior. One theory posits that dopaminergic signaling in the striatum during reward conditioning leads to changes in visual cortical and parietal representations of the stimulus used, and this, in turn, sustains attentional bias even when reward is discontinued. However, only a few studies have examined neural activity during both rewarded and unrewarded task phases.
UNASSIGNED: In the current study, participants first completed a reward-conditioning phase, during which responses to certain stimuli were associated with monetary reward. These stimuli were then included as non-predictive cues in a spatial cueing task. Participants underwent functional brain imaging during both task phases.
UNASSIGNED: The results show that striatal activity during the learning phase predicted increased visual cortical and parietal activity and decreased ventro-medial prefrontal cortex activity in response to conditioned stimuli during the test. Striatal activity was also associated with anterior cingulate cortex activation when the reward-conditioned stimulus directed attention away from the target.
UNASSIGNED: Our findings suggest that striatal activity during reward conditioning predicts the degree to which reward history biases attention through learning-induced changes in visual and parietal activities.
UNASSIGNED: In the current study, participants first completed a reward-conditioning phase, during which responses to certain stimuli were associated with monetary reward. These stimuli were then included as non-predictive cues in a spatial cueing task. Participants underwent functional brain imaging during both task phases.
UNASSIGNED: The results show that striatal activity during the learning phase predicted increased visual cortical and parietal activity and decreased ventro-medial prefrontal cortex activity in response to conditioned stimuli during the test. Striatal activity was also associated with anterior cingulate cortex activation when the reward-conditioned stimulus directed attention away from the target.
UNASSIGNED: Our findings suggest that striatal activity during reward conditioning predicts the degree to which reward history biases attention through learning-induced changes in visual and parietal activities.
摘要：
■即使干扰目标驱动的行为，对奖励相关刺激的注意偏差也会发生。一种理论认为，在奖赏调节过程中纹状体中的多巴胺能信号会导致所使用刺激的视觉皮层和顶叶表征发生变化，而这个,反过来,即使奖励停止，也能维持注意力偏见。然而,只有少数研究检查了有奖励和无奖励任务阶段的神经活动。
■在当前的研究中，参与者首先完成了奖励调节阶段，在此期间，对某些刺激的反应与金钱奖励有关。然后将这些刺激作为非预测性提示包括在空间提示任务中。参与者在两个任务阶段都接受了功能性脑成像。
■结果表明，学习阶段的纹状体活动预测了视觉皮层和顶叶活动的增加，并在测试过程中响应条件刺激而降低了腹内侧前额叶皮层活动。当奖赏条件刺激使注意力远离目标时，纹状体活动也与前扣带回皮层激活有关。
■我们的发现表明，奖赏调节过程中的纹状体活动通过学习引起的视觉和顶叶活动变化来预测奖赏史使注意力偏向的程度。
■在当前的研究中，参与者首先完成了奖励调节阶段，在此期间，对某些刺激的反应与金钱奖励有关。然后将这些刺激作为非预测性提示包括在空间提示任务中。参与者在两个任务阶段都接受了功能性脑成像。
■结果表明，学习阶段的纹状体活动预测了视觉皮层和顶叶活动的增加，并在测试过程中响应条件刺激而降低了腹内侧前额叶皮层活动。当奖赏条件刺激使注意力远离目标时，纹状体活动也与前扣带回皮层激活有关。
■我们的发现表明，奖赏调节过程中的纹状体活动通过学习引起的视觉和顶叶活动变化来预测奖赏史使注意力偏向的程度。
