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Abstract：
Recent advances in high-throughput proteomic profiling technologies have facilitated the precise quantification of numerous proteins across multiple specimens concurrently. Researchers have the opportunity to comprehensively analyze the molecular signatures in plentiful medical specimens or disease pattern cell lines. Along with advances in data analysis and integration, proteomics data could be efficiently consolidated and employed to recognize precise elementary molecular mechanisms and decode individual biomarkers, guiding the precision treatment of tumors. Herein, we review a broad array of proteomics technologies and the progress and methods for the integration of proteomics data and further discuss how to better merge proteomics in precision medicine and clinical settings.
摘要：
高通量蛋白质组学分析技术的最新进展有助于同时对多个样本中的多种蛋白质进行精确定量。研究人员有机会全面分析大量医学标本或疾病模式细胞系中的分子特征。随着数据分析和集成的进步，蛋白质组学数据可以有效地巩固和利用，以识别精确的基本分子机制和解码个体生物标志物，指导肿瘤的精准治疗。在这里，我们回顾了广泛的蛋白质组学技术以及蛋白质组学数据整合的进展和方法，并进一步讨论了如何在精准医学和临床环境中更好地合并蛋白质组学。
