PDF(Pubmed)
Abstract：
The prevalence of isolated systolic hypertension (ISH) has doubled between 2002-2005 and 2014 among the oldest-old population in China. However, the prevalence and characteristics of ISH among the oldest-old population in southwestern China remain less known. This study aimed to investigate the prevalence of ISH among the oldest-old population in Chengdu and identify associated factors to provide valuable information for disease etiology and prevention. We recruited 1,312 participants aged over 80 years by using a stratified cluster sampling method between September 2015 and June 2016, from three districts (Jinjiang, Qingyang, and Longquanyi) of Chengdu, the largest city of southwest China. A structured questionnaire, anthropometric data, and blood pressure were collected according to the standard method. Blood pressure was measured three times by using a standardized mercury sphygmomanometer after a 10-minute seated rest. Of 1312 participants, 53.0% (n = 695) had ISH. The prevalence of ISH in men and women was 54.7% and 51.3%, respectively, with no significant sex difference (P = .222). The prevalence of ISH increased with advanced age in men (P for trend = 0.029), 52.5% for the 80-84 years group, 55.2% for the 85-89 years group, and 70.4% for the 90-98 years group, respectively. Multivariable logistic regression analyses found that drinking (OR = 1.85, 95%CI = 1.26-2.71), being overweight (OR = 1.88, 95%CI = 1.19-2.96), and having a higher heart rate (OR = 0.66, 95%CI = 0.51-0.86) were associated with ISH. Stratified by sex, these three factors remained significant in men. Our work highlights that the burden of ISH is substantial among the oldest-old population in southwestern China.
摘要：
在中国年龄最大的老年人群中，单纯收缩期高血压（ISH）的患病率在2002-2005年至2014年之间翻了一番。然而,在中国西南地区最古老的老年人群中，ISH的患病率和特征仍然鲜为人知。本研究旨在调查成都市高龄老年人群ISH的患病率，并找出相关因素，为该病的病因和预防提供有价值的信息。我们在2015年9月至2016年6月之间采用分层整群抽样方法，从三个地区（晋江，庆阳,和成都的龙泉驿站)，中国西南最大的城市。结构化问卷，人体测量数据,并按标准方法采集血压。休息10分钟后，使用标准化的水银血压计测量血压3次。在1312名参与者中，53.0%(n=695)患有ISH。男性和女性的ISH患病率分别为54.7%和51.3%,分别,无显著性别差异(P=0.222)。男性ISH的患病率随着年龄的增长而增加（趋势P=0.029），80-84岁组的52.5%，85-89岁组的55.2%，90-98岁组的70.4%，分别。多变量Logistic回归分析发现，饮酒(OR=1.85，95CI=1.26-2.71)，超重（OR=1.88，95CI=1.19-2.96），心率较高(OR=0.66,95CI=0.51-0.86)与ISH相关。按性别分层，这三个因素在男性中仍然很重要。我们的工作强调，在中国西南部最古老的人口中，ISH的负担是巨大的。
