PDF(Pubmed)
Abstract：
Nairoviridae is a family for negative-sense RNA viruses with genomes of about 17.2-21.1 kb. These viruses are maintained in and/or transmitted by arthropods among birds, reptiles and mammals. Norwaviruses and orthonairoviruses can cause febrile illness in humans. Several orthonairoviruses can infect mammals, causing mild, severe and sometimes, fatal diseases. Nairovirids produce enveloped virions containing two or three single-stranded RNA segments with open reading frames that encode a nucleoprotein (N), sometimes a glycoprotein precursor (GPC), and a large (L) protein containing an RNA-directed RNA polymerase (RdRP) domain. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) report on the family Nairoviridae, which is available at www.ictv.global/report/nairoviridae.
摘要：
Nairoviridae是负义RNA病毒的家族，基因组约为17.2-21.1kb。这些病毒在鸟类中保存和/或由节肢动物传播，爬行动物和哺乳动物。Norwaviruses和orthonairovirus可引起人类高热疾病。几种正交病毒可以感染哺乳动物，导致温和，严重，有时，致命的疾病。Nairovirids产生包膜病毒粒子，包含两个或三个单链RNA片段，具有编码核蛋白（N）的开放阅读框，有时是糖蛋白前体(GPC)，和含有RNA指导的RNA聚合酶(RdRP)结构域的大(L)蛋白。这是国际病毒分类学委员会（ICTV）关于奈罗氏病毒科的报告的摘要，可以在www上找到。ictv。全球/报告/nairoviridae.
