Abstract：
OBJECTIVE: To characterize the diagnostic yield of patients undergoing evaluation for superior canal dehiscence syndrome (SCDS), and identify alternative conditions diagnosed in patients suspected of, but not ultimately diagnosed with, SCDS.
METHODS: Diagnostically undifferentiated adult patients suspected of having SCDS were identified between 2016 and 2021 at a tertiary academic medical system. Patients were categorized by diagnostic testing, radiographic superior semicircular canal (SSC) abnormality, symptoms, evaluating clinician specialty, operative intervention, and diagnosis. Differences among groups were assessed for statistical significance.
RESULTS: Of 1242 candidate patients, 477 met inclusion criteria-evaluation by a clinician with SCDS on their differential diagnosis prior to diagnostic imaging. The mean (SD) age was 53.0 (15.0) years and 70.6% were female. A total of 364 patients underwent subsequent diagnostic imaging, and among these, 164 (45.1%) had a radiographic SSC abnormality with 99 (27.2%) receiving a diagnosis of SCDS (two cases of \"near dehiscence syndrome\"). One third (33.3%) of patients with SCDS underwent operative repair. Most clinicians with the initial suspicion for SCDS were otolaryngologists (90.6%), who had greater diagnostic yield than clinicians from other specialties (22.2% vs. 6.7%, p = 0.012). Patients not diagnosed with SCDS alternatively received 21 unique diagnoses and 52.1% (138/265) were not definitively diagnosed with any condition.
CONCLUSIONS: This study characterizes the diagnostic incidence, or yield, of newly identified radiographic SSC abnormalities (45.1%) and SCDS (27.2%) among people suspected of having SCDS. Considerable overlap in presentation between SCDS and other conditions exists, and there is need for improvement in efficiently diagnosing patients with SCDS and audio-vestibular complaints in general.
METHODS: III Laryngoscope, 134:4095-4100, 2024.
METHODS: Diagnostically undifferentiated adult patients suspected of having SCDS were identified between 2016 and 2021 at a tertiary academic medical system. Patients were categorized by diagnostic testing, radiographic superior semicircular canal (SSC) abnormality, symptoms, evaluating clinician specialty, operative intervention, and diagnosis. Differences among groups were assessed for statistical significance.
RESULTS: Of 1242 candidate patients, 477 met inclusion criteria-evaluation by a clinician with SCDS on their differential diagnosis prior to diagnostic imaging. The mean (SD) age was 53.0 (15.0) years and 70.6% were female. A total of 364 patients underwent subsequent diagnostic imaging, and among these, 164 (45.1%) had a radiographic SSC abnormality with 99 (27.2%) receiving a diagnosis of SCDS (two cases of \"near dehiscence syndrome\"). One third (33.3%) of patients with SCDS underwent operative repair. Most clinicians with the initial suspicion for SCDS were otolaryngologists (90.6%), who had greater diagnostic yield than clinicians from other specialties (22.2% vs. 6.7%, p = 0.012). Patients not diagnosed with SCDS alternatively received 21 unique diagnoses and 52.1% (138/265) were not definitively diagnosed with any condition.
CONCLUSIONS: This study characterizes the diagnostic incidence, or yield, of newly identified radiographic SSC abnormalities (45.1%) and SCDS (27.2%) among people suspected of having SCDS. Considerable overlap in presentation between SCDS and other conditions exists, and there is need for improvement in efficiently diagnosing patients with SCDS and audio-vestibular complaints in general.
METHODS: III Laryngoscope, 134:4095-4100, 2024.
摘要：
目的：描述接受上管裂开综合征（SCDS）评估的患者的诊断率，并确定在怀疑的患者中诊断出的替代条件，但最终没有被诊断出，SCDS。
方法：在2016年至2021年之间，在三级学术医疗系统中确定了疑似患有SCDS的诊断未分化成年患者。通过诊断测试对患者进行分类，影像学上半规管（SSC）异常，症状,评估临床医师专业，手术干预，和诊断。评估组间差异的统计学意义。
结果：在1242名候选患者中，477符合纳入标准-由SCDS的临床医生在诊断成像之前对其鉴别诊断进行评估。平均（SD）年龄为53.0（15.0）岁，女性占70.6％。总共364名患者接受了随后的诊断成像，其中，164例（45.1％）有放射学SSC异常，其中99例（27.2％）接受了SCDS诊断（2例“近裂开综合征”）。三分之一（33.3％）的SCDS患者接受了手术修复。大多数最初怀疑SCDS的临床医生是耳鼻喉科医师（90.6%），谁比其他专业的临床医生有更高的诊断率(22.2%vs.6.7%,p=0.012)。未诊断为SCDS的患者接受了21种独特的诊断，52.1％（138/265）未明确诊断为任何疾病。
结论：这项研究描述了诊断发病率，或产量，在怀疑患有SCDS的人群中，新发现的影像学SSC异常（45.1％）和SCDS（27.2％）。SCDS和其他条件之间的显示存在相当大的重叠，并且需要改进对SCDS和音频前庭主诉患者的有效诊断。
方法：III喉镜，2024.
方法：在2016年至2021年之间，在三级学术医疗系统中确定了疑似患有SCDS的诊断未分化成年患者。通过诊断测试对患者进行分类，影像学上半规管（SSC）异常，症状,评估临床医师专业，手术干预，和诊断。评估组间差异的统计学意义。
结果：在1242名候选患者中，477符合纳入标准-由SCDS的临床医生在诊断成像之前对其鉴别诊断进行评估。平均（SD）年龄为53.0（15.0）岁，女性占70.6％。总共364名患者接受了随后的诊断成像，其中，164例（45.1％）有放射学SSC异常，其中99例（27.2％）接受了SCDS诊断（2例“近裂开综合征”）。三分之一（33.3％）的SCDS患者接受了手术修复。大多数最初怀疑SCDS的临床医生是耳鼻喉科医师（90.6%），谁比其他专业的临床医生有更高的诊断率(22.2%vs.6.7%,p=0.012)。未诊断为SCDS的患者接受了21种独特的诊断，52.1％（138/265）未明确诊断为任何疾病。
结论：这项研究描述了诊断发病率，或产量，在怀疑患有SCDS的人群中，新发现的影像学SSC异常（45.1％）和SCDS（27.2％）。SCDS和其他条件之间的显示存在相当大的重叠，并且需要改进对SCDS和音频前庭主诉患者的有效诊断。
方法：III喉镜，2024.
