Abstract：
Adult mechanical bowel obstruction (AMBO) has been previously reported to be majorly caused by hernias in developing countries. In Nigeria, however, there has been a recent change in pattern with adhesions now being the leading cause. The aim of this systematic review is to examine the changing pattern of the causes, and outcomes of patients managed for AMBO in Nigeria.
Relevant keywords relating to AMBO were used to conduct a search on PubMed, Web of Science, Google Scholar, and AJOL. The search returned 507 articles, which were subjected to title, abstract, and full text screenings, according to the inclusion and exclusion criteria. This generated 10 articles which were included in the final qualitative synthesis.
The total sample size across the 10 studies was 1033. Adhesions, hernias, and intra-abdominal tumors, responsible for 46.25%, 26.31%, and 12.23% of cases respectively, were the major causes of AMBO in Nigeria. 65.6% of cases were managed operatively and 34.4% were managed conservatively. The meta-analysis revealed high morbidity and mortality rates of 31% (95% CI: 17; 44, 5) and 11% (95% CI: 6; 15, 5), respectively, among adult patients managed for mechanical bowel obstruction in Nigeria.
Adhesion, which results predominantly from appendicectomy is the most common cause of AMBO in Nigeria. This is unlike former reports where hernia was the most common cause. Morbidity results majorly from wound infection, recurrent adhesions, and postoperative enterocutaneous fistula. The mortality rate is similar to reports from various West African studies, and it is significantly influenced by surgical intervention time.
Relevant keywords relating to AMBO were used to conduct a search on PubMed, Web of Science, Google Scholar, and AJOL. The search returned 507 articles, which were subjected to title, abstract, and full text screenings, according to the inclusion and exclusion criteria. This generated 10 articles which were included in the final qualitative synthesis.
The total sample size across the 10 studies was 1033. Adhesions, hernias, and intra-abdominal tumors, responsible for 46.25%, 26.31%, and 12.23% of cases respectively, were the major causes of AMBO in Nigeria. 65.6% of cases were managed operatively and 34.4% were managed conservatively. The meta-analysis revealed high morbidity and mortality rates of 31% (95% CI: 17; 44, 5) and 11% (95% CI: 6; 15, 5), respectively, among adult patients managed for mechanical bowel obstruction in Nigeria.
Adhesion, which results predominantly from appendicectomy is the most common cause of AMBO in Nigeria. This is unlike former reports where hernia was the most common cause. Morbidity results majorly from wound infection, recurrent adhesions, and postoperative enterocutaneous fistula. The mortality rate is similar to reports from various West African studies, and it is significantly influenced by surgical intervention time.
摘要：
背景：先前已报道成人机械性肠梗阻（AMBO）在发展中国家主要由疝引起。在尼日利亚,然而,最近模式发生了变化，粘连现在是主要原因。这次系统回顾的目的是研究原因的变化模式，以及在尼日利亚接受AMBO治疗的患者的结果。
方法：使用与AMBO相关的关键词在PubMed上进行搜索，WebofScience,谷歌学者，和AJOL。搜索返回507篇文章，受到标题的影响，abstract,和全文放映，根据纳入和排除标准。这产生了10篇文章，这些文章被包括在最终的定性综合中。
结果：10项研究的总样本量为1033。粘连,疝气,和腹内肿瘤，占46.25%，26.31%,分别占12.23%,是尼日利亚AMBO的主要原因。65.6％的病例得到了手术管理，34.4％的病例得到了保守管理。荟萃分析显示高发病率和死亡率为31%(95%CI:17;44,5)和11%(95%CI:6;15,5),分别,在尼日利亚治疗机械性肠梗阻的成年患者中。
结论：附着力，主要来自阑尾切除术的结果是尼日利亚AMBO的最常见原因。这与以前的报告不同，以前的报告是最常见的原因。发病率主要由伤口感染引起，复发性粘连,和术后肠外瘘。死亡率与各种西非研究的报告相似，并且受手术干预时间的影响很大。
方法：使用与AMBO相关的关键词在PubMed上进行搜索，WebofScience,谷歌学者，和AJOL。搜索返回507篇文章，受到标题的影响，abstract,和全文放映，根据纳入和排除标准。这产生了10篇文章，这些文章被包括在最终的定性综合中。
结果：10项研究的总样本量为1033。粘连,疝气,和腹内肿瘤，占46.25%，26.31%,分别占12.23%,是尼日利亚AMBO的主要原因。65.6％的病例得到了手术管理，34.4％的病例得到了保守管理。荟萃分析显示高发病率和死亡率为31%(95%CI:17;44,5)和11%(95%CI:6;15,5),分别,在尼日利亚治疗机械性肠梗阻的成年患者中。
结论：附着力，主要来自阑尾切除术的结果是尼日利亚AMBO的最常见原因。这与以前的报告不同，以前的报告是最常见的原因。发病率主要由伤口感染引起，复发性粘连,和术后肠外瘘。死亡率与各种西非研究的报告相似，并且受手术干预时间的影响很大。
